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What Causes Diarrhea After Taking Antibiotics For Treatment Of Clostridium Difficile?

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Posted on Tue, 9 Dec 2014
Question: I have had c diff test positive twice. After antibiotics I have also been on Welchol 625mg x 3 times daily. I have over the past months developed off and on diarrhea. Do you think this could be c diff back or would the diarrhea be vicious by now if I had c diff?
doctor
Answered by Dr. Ivo Ditah (23 minutes later)
Brief Answer:
The diarrhea should be vicious by now!

Detailed Answer:
Hi and thank you so much for this query.

I am so sorry to hear about this cdiff and the diarrhea that you have reported. This diarrhea is not typical of cdiff as I would have expected it to be more vicious than this. The on/off nature may be a side effect of Welchol. Welchol has diarrhea as a recognized side effect. Ask you doctor about this and hear what he says. He may want to consider other lipids lowering drugs if this diarrhea is very worrisome. If it is mild, then I will say put up and carry on with the treatment.

I hope this helps. I wish you well. Thank you so much for using our services and feel free to ask for more information and clarifications if need be.
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
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Follow up: Dr. Ivo Ditah (28 hours later)
I take Welchol to stop my diarrhea. So Welchol would not stop c diff? Is that what you are saying. So if I had c diff even on Welchol that is supposed to stop diarrhea my diarrhea would be profuse? Thanks for answering so promptly!
doctor
Answered by Dr. Ivo Ditah (1 hour later)
Brief Answer:
Have you had gall blader surgery?

Detailed Answer:
Hi,

Why would you be taking Welchol for diarrhea. Have you had your gal bladder removed? Welchol has no effect on cdiff and cannot mitigate its symptoms. Welchol stops diarrhea by a mechanism that has just nothing to do with the way cdiff causes diarrhea.


I hope this helps and I wish you well.

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
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Follow up: Dr. Ivo Ditah (41 minutes later)
Yes i had my gallbladder removed about 15 months ago.
doctor
Answered by Dr. Ivo Ditah (37 minutes later)
Brief Answer:
Okay...makes sense!

Detailed Answer:
Hi,

I now understand the reasons for the welchol. If you have further issues that you would like us to talk to talk on at this time, please bring them to my attention.

Else, keep me updated with your progress. Your diarrhea is likely related to the gall bladder surgery and maybe not Cdiff.


I wish you well.
Note: For further follow up on digestive issues share your reports here and Click here.

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
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Answered by
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Dr. Ivo Ditah

Internal Medicine Specialist

Practicing since :2002

Answered : 3984 Questions

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What Causes Diarrhea After Taking Antibiotics For Treatment Of Clostridium Difficile?

Brief Answer: The diarrhea should be vicious by now! Detailed Answer: Hi and thank you so much for this query. I am so sorry to hear about this cdiff and the diarrhea that you have reported. This diarrhea is not typical of cdiff as I would have expected it to be more vicious than this. The on/off nature may be a side effect of Welchol. Welchol has diarrhea as a recognized side effect. Ask you doctor about this and hear what he says. He may want to consider other lipids lowering drugs if this diarrhea is very worrisome. If it is mild, then I will say put up and carry on with the treatment. I hope this helps. I wish you well. Thank you so much for using our services and feel free to ask for more information and clarifications if need be.