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What are the side effects of paracetamol, diclofenac sodium and chlorzoxazone if taken together?

Feb 2014
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Orthopaedic Surgeon, Joint Replacement
Practicing since : 2004
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i would like to know the possible adverse effects if paracetamol, diclofenac sodium and chlorzoxazone are taken together. Also does this combination in the form of FDC is rational ? please comment.
Posted Fri, 2 Nov 2012 in Medicines and Side Effects
Answered by Dr. Saurabh Gupta 3 hours later

Thanks for posting your query.

Possible adverse effect of this combination-

Drowsiness, dizziness, lightheadedness, headache, excitement, restlessness, GI disturbances, irritability, sensitivity reactions (skin rash). Jaundice, liver damage reported, Orange or reddish-purple urine.

This combination in form of FDC is not rationale.

Hope I have answered your query. Let me know if you have any more concerns.

If you have no more queries, please accept my answer, rate and give reviews.

Wishing you good health.
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