Get your health question answered instantly from our pool of 18000+ doctors from over 80 specialties

173 Doctors Online
Doctor Image
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

I will be looking into your question and guiding you through the process. Please write your question below.

Took short course of oxandrolone long back. Responsible for indigenous testosterone secretion now?

Answered by
Dr.
Dr. Michelle Gibson James

General & Family Physician

Practicing since :2001

Answered : 15761 Questions

default
Posted on Thu, 17 Jan 2013 in Medicines and Side Effects
Question: I have a queston regarding short oxandrolone course i took when i14 and half years old. Is the oxandrolone therapy i underwent long time ago still responsible for my indigenous testosterone secretion NOW in adulthood??
doctor
Answered by Dr. Michelle Gibson James 2 days later
Hi, thanks for using healthcare magic

Oxandrolone is an anabolic steroid which is a manufactured form of testosterone.
It is not thought to have a significant impact on testosterone levels at low doses.

There is a part of the brain called the pituitary that produces hormones that sends messages to the testes telling it to make testosterone.If the level of testosterone becomes too high, then a feed back message is relayed to this part of the brain telling it to stop stimulating the testes- this results in decreased testosterone production.

Because oxandrolone is a synthetic testosterone, the body may believe that there is elevated levels of testosterone.As a result there would be decreased stimulation of the testes to produce testosterone.This decreased stimulation can potentially result in atrophy (shrinking) of the testes.
If there is decreased size then this would potentially affect future production of testosterone.

If the dose was low , which is likely was since you were so young, and the course short then it is unlikely that the above would have occurred.

Hope this helps, feel free to ask any other questions
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
default
Follow up: Dr. Michelle Gibson James 39 hours later
Thank you Dr XXXXXXX ,

How about its effects on HPG axis ....does a short course of anabolic steroids taken during childhood (early stages of HPG maturation) have any 'lasting' legay on future fully activated HPG axis??

Or is this wrong logic to ?

doctor
Answered by Dr. Michelle Gibson James 8 hours later
Hi, the axis is influenced by the present level of hormones. It operates on a feed back mechanism , so the levels of the hormones secreted by the hypothalamus and pituitary are influenced by the level of hormones made in the end organs.


Feel free to ask anything else
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
premium_optimized

The User accepted the expert's answer

Share on
Question is related to
Drug/Medication ,   ,   ,  
Medical Topics

Recent questions on  Neuroendocrinology

doctor1 MD

dear sir,i am 35 year old. having the ED problem since form 2 year, as i consulated with doctor, they have tested me the sugar BP & TESTOSTERONE (FREE) found evernting normal. and suggested me the Nano leo cap twice a day for three month. Kindly requesting to give us the suggescation regarding this .

doctor1 MD

im 24 years old, my left testical is removed. my testosterone level is low and high prolactine. i can't maintain long erection during sex and my doctor start giving me testoviron depot 250 mg injection and i dont feel any difference, what should i do ?

doctor1 MD

HI Doctor! I was on testosterone injections for a year and My level fell to 79! My question if I stop injections can my level increase to normal range and what is a normal range? And is it dangerous for me to stop? My age is 52! Also is there any cheaper routes I ve moved from my old address and the doctors here want me to come in and pay for a shot instead of doing it myself!?

doctor1 MD

i AM AN 82 YEAR OLD MALE. MY PLATELET COUNT IS 30. MY ENDOCRONOLOGIST ADVISED ME TO TAKE TESTOSTERONE EVERY 2 WEEKS TO FEEL STRONGER & MORE ALIVE. HOWEVER, MY HEMATOLOGIST SAYS IT IS LOWERING THE PLATELET COUNT, AS i HAVE ITP. IS IT IN FACT DANGEROUS TO CONTINUE THE TESTOSTERONE SHOTS? I ALSO HAVE FIBRILATION - UNEVEN HEART BEAT. ALSO, I HAD A STROKE ABOUT 10 YEARS AGO. I WOULD APPRECIATE AN OPINION.

doctor1 MD

Hi. When I was younger I had steroid treatment to increase my height, as steroid is known to increase growth hormones in adolescent boys. Now I have anxiety this treatment had effect on my bone, and the effects are permanent. Do bones renew and...

doctor1 MD

I take.10 synthroid and .15 hydrocortisone daily. I recently had blood test and cortisone without meds was .6 and my Free T4 was low at .98. I have suffered for over 1.5 months with dry mouth syndrome . I saw an ENT who told me to suck on lemon...

doctor1 MD

I, my name is XXXXXXX 45 years old, recently i was diagnosed by my doctor to have mood disorder with depression due to stress and fatigue from work... That result in a 3 1/2 months stop from work. Then he prescrided me this medication you must...