Sign-in to Ask A Doctor - 24x7
OR
Sign in with Google
Suggest Treatment For Skin Problem And Fatigue
Question: I have RA and a recent Myositis-Specific AB Panel shows that my Jo-1 Antibody, IgG is significantly out of the standard range. My number is 247 compared to the standard 0-40 AU/mL. Can you tell me what this means and what I might do to bring the number into standard. I am having skin problems with my hands and am wondering if this test result is suggesting why. Thank you for your help.
Brief Answer:
? myositis
Detailed Answer:
Good evening.
Thank you for writing on health care magic
Well there are a few questions which I would like to know to relate your symptoms to the positive antibody:
1. What kind of skin problems are you experiencing, is it rashes over the knuckles,,face and elbows or something else
2. Do you experience any fatigue in the muscles after mild exertion?
3. Do you have any difficulty in climbing stairs or getting up from toilet seat?
4. Any difficulty in combing hair
5/ any history of cough or breathing difficulty?
6. Any bluish discoloration of the fingers on cold exposure?
Anti XXXXXXX 1 is a antibody specific for myositis. That is inflammation of the muscles. But yes you need to have symptoms along with it before we can start treatment for it. Myositis and rheumatoid arthritis overlap are very common.but we have to treat the symptoms than antibody.
Also if you could let me know your medications for rheumatoid that would be helpful.
Await your reply
Regards
Dr naval
? myositis
Detailed Answer:
Good evening.
Thank you for writing on health care magic
Well there are a few questions which I would like to know to relate your symptoms to the positive antibody:
1. What kind of skin problems are you experiencing, is it rashes over the knuckles,,face and elbows or something else
2. Do you experience any fatigue in the muscles after mild exertion?
3. Do you have any difficulty in climbing stairs or getting up from toilet seat?
4. Any difficulty in combing hair
5/ any history of cough or breathing difficulty?
6. Any bluish discoloration of the fingers on cold exposure?
Anti XXXXXXX 1 is a antibody specific for myositis. That is inflammation of the muscles. But yes you need to have symptoms along with it before we can start treatment for it. Myositis and rheumatoid arthritis overlap are very common.but we have to treat the symptoms than antibody.
Also if you could let me know your medications for rheumatoid that would be helpful.
Await your reply
Regards
Dr naval
Above answer was peer-reviewed by :
Dr. Yogesh D
1. Confined to fingers on both hands. Continually experiencing very rough and scaly skin and split fingers which keep recurring even after healed with various types of hand creams.
2.- 5. None of these symptoms at this time.
6. Fingers quickly turn white on the ends when exposed to cold.
Meds: Orencia (Abatacept) injections, 125 mg and methotraxate 6 tablets 2.5 mg once a week.
2.- 5. None of these symptoms at this time.
6. Fingers quickly turn white on the ends when exposed to cold.
Meds: Orencia (Abatacept) injections, 125 mg and methotraxate 6 tablets 2.5 mg once a week.
Brief Answer:
Significance of XXXXXXX 1 Positivity
Detailed Answer:
Good evening
Well the skin problems you are experiencing don’t seem to fit in with XXXXXXX 1 positivity. But yes the whitish discoloration of fingers on cold exposure does. It is called as Raynuads phenomeon. Due to narrowing of the blood vessels on cold exposure, not enough blood reaches the fingers.
As your XXXXXXX 1 is positive but you are not experiencing any muscle symptoms, I would still advise you to get CPK, LDH, SGOT, SGPT and Serum Aldolase levels along with a Chest x Ray done to detect any ongoing activity of the muscles which has not surfaced yet.
Just having Antibody positivity doesn't mean we need to treat it. We need to treat your symptoms predominantly. For raynauds, I will suggest you consult your Rheumatologist and consider starting Tablet nifedipine 10 mg twice daily.
If any of the muscle enzymes come positive, we will need to start you on medium dose of steroids (0.5 mg/kg). If they are normal, you need not worry about it too much
Hope the information was useful
Do let me know for more queries
Regards
Dr Naval
Significance of XXXXXXX 1 Positivity
Detailed Answer:
Good evening
Well the skin problems you are experiencing don’t seem to fit in with XXXXXXX 1 positivity. But yes the whitish discoloration of fingers on cold exposure does. It is called as Raynuads phenomeon. Due to narrowing of the blood vessels on cold exposure, not enough blood reaches the fingers.
As your XXXXXXX 1 is positive but you are not experiencing any muscle symptoms, I would still advise you to get CPK, LDH, SGOT, SGPT and Serum Aldolase levels along with a Chest x Ray done to detect any ongoing activity of the muscles which has not surfaced yet.
Just having Antibody positivity doesn't mean we need to treat it. We need to treat your symptoms predominantly. For raynauds, I will suggest you consult your Rheumatologist and consider starting Tablet nifedipine 10 mg twice daily.
If any of the muscle enzymes come positive, we will need to start you on medium dose of steroids (0.5 mg/kg). If they are normal, you need not worry about it too much
Hope the information was useful
Do let me know for more queries
Regards
Dr Naval
Note: For further information on diet changes to reduce allergy symptoms or to boost your immunity, Ask here.
Above answer was peer-reviewed by :
Dr. Bhagyalaxmi Nalaparaju
Answered by
Get personalised answers from verified doctor in minutes across 80+ specialties
