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Slightly Elevated RDW (46.8), Monocytes 12.5%, (abs .7), Serum Protein

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Posted on Sat, 13 Apr 2019
Question: Slightly elevated RDW (46.8), Monocytes 12.5%, (abs .7), Serum Protein 60. A/G ration 2.8, albumin 43. Male, 65 years old. The monocytes % have been slowly increasing over the past several years from 10%. The protein has always been low or low normal, 66, etc. Had a D-Dimer scare last year of 1800. Last check, it had fallen to 920.

Should I be worried about CMML or some other neoplasm?
                                                       
doctor
Answered by Dr. Dr. Esmeralda Sera (42 minutes later)
Brief Answer:
Blood exams

Detailed Answer:
Hello and thank you for asking

Diagnosing chronic myelomonocytic leukemia (CMML) or other neoplasms usually involves a series of repeated tests, including blood and bone marrow tests. Your doctor usually can't confirm a diagnosis of CMML with one lab test result that shows abnormal blood counts

In my opinion you should not worry with this blood tests for malignancy.
Have you other health issues ore are you under treatment with medication please?

Feel free for asking further
Above answer was peer-reviewed by : Dr. Yogesh D
doctor
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Follow up: Dr. Dr. Esmeralda Sera (55 minutes later)
Hello Dr. Sera,

Thank you or your kind response. So, you really see nothing worrying?

As to your question: I sent along another document that lists my conditions, hypertension, pre-diabetes. It should be available now.

I really worry because I just can't find any good (fixable) reasons for the high A/G ratio and low Immunoglobulins. (I was taking quite a bit of NSAIDS for arthritis and muscle pain at the time, but have stopped). And, other than the high Monocytes differential, and RDW-SD, things seem quite good.

As an elevated D-Dimer can also indicate the presence of malignancies, (I was checked very thoroughly for blood clots at the time it hit 2000), but it has fallen since then. I take a baby aspirin daily.

In April of 2018, I had my leg varicose veins stripped. Again, I would have thought that the blood values would have normalized by then.

That's all, I guess. I'll have another full workup in May, but i haven't slept well since I consulted "Dr. Google" about monocytosis and elevated AG/R. Although I am 65, MANY people depend upon me and my income for their lives, and I worry alot about letting them down.

Sincerely,
XXXXXXX "Goblush"
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Follow up: Dr. Dr. Esmeralda Sera (2 minutes later)
I should have mentioned: I also had a complete Gastro-and Colonoscopy exam, PSA, Chest Xrays, etc, to rule out any obvious cancer. My mom had BC and ad died from PC, you see, so I won the genetic lottery.
doctor
Answered by Dr. Dr. Esmeralda Sera (12 minutes later)
Brief Answer:
Blood counts

Detailed Answer:
Hello again

As you said you suffer from autoimmune disease like arthritis witch is one of the reason of those test results, high A/G ratio an low Immunoglobulin levels.

I think that you have not to worry about neoplasms,i will suggest you to repeat the tests after 4-6 weeks
Above answer was peer-reviewed by : Dr. Yogesh D
doctor
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Follow up: Dr. Dr. Esmeralda Sera (12 minutes later)
Very well, Doctor. That I shall do!

σου εύχομαι μια καλή μέρα!

Regards!

doctor
Answered by Dr. Dr. Esmeralda Sera (1 minute later)
Brief Answer:
regarding the blood tests

Detailed Answer:
Thank you very much, you too...

Take care

Note: Do you have more questions on diagnosis or treatment of blood disorders? Ask An Expert/ Specialist Now

Above answer was peer-reviewed by : Dr. Arnab Banerjee
doctor
Answered by
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Dr. Dr. Esmeralda Sera

Oncologist

Practicing since :1998

Answered : 1375 Questions

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Slightly Elevated RDW (46.8), Monocytes 12.5%, (abs .7), Serum Protein

Brief Answer: Blood exams Detailed Answer: Hello and thank you for asking Diagnosing chronic myelomonocytic leukemia (CMML) or other neoplasms usually involves a series of repeated tests, including blood and bone marrow tests. Your doctor usually can't confirm a diagnosis of CMML with one lab test result that shows abnormal blood counts In my opinion you should not worry with this blood tests for malignancy. Have you other health issues ore are you under treatment with medication please? Feel free for asking further