Get your health question answered instantly from our pool of 18000+ doctors from over 80 specialties

132 Doctors Online
Doctor Image
Dr. Andrew Rynne

Family Physician

Exp 50 years

I will be looking into your question and guiding you through the process. Please write your question below.

Is negative HerpeSelect IgG test after 14 weeks of exposure conclusive?

Answered by
Dr. Kakkar S.


Practicing since :2002

Answered : 8397 Questions

Posted on Mon, 9 Nov 2015 in Sexually Transmitted Diseases
Question: I recently got a IGG herpeselect test from Quest after 14 weeks of exposure. Both HSV 1 and 2 came back <0.9 (Negative).

However, I am concerned that I still may have herpes in my blood but it is just too early to detect. Should I repeat the testing at 6 months. Is it possible to get an exact number (i.e 0.2) instead of just "less than 0.9"

Also, what does this index number mean, and is it possible to have an index number of 0?
Answered by Dr. Kakkar S. 1 hour later
Brief Answer:
You don't have herpes

Detailed Answer:
Hello. Thank you for writing to us

A negative HSV IgG after 12 weeks of exposure is conclusive and rules out herpes infection.
Index value can be an exact number and some tests do report it as an exact number (e.g 0.2, 0.5 etc) however, as long as it is 'less than 0.9' it is negative.
Index values, are really only to tell whether you have detectable antibody or you don’t have detectable antibody therefore an index value that may not be 'Zero' but 'less than 0.9' does'nt mean that you have a low level herpes infection or early herpes infection, it simply means you don't have detectable antibodies related to herpes infection. Therefore if this test was done after an adequate time interval of exposure (usually taken as 12 weeks for IgG antibodies to appear after infection) and index value of IgG was 'less than 0.9' it is taken as negative i.e you don't have antibodies.

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
Follow up: Dr. Kakkar S. 3 hours later
Thank you so much for the reply (and relief) Doctor. So do you think it would be redundant to test again after 6 months, or would it be a good precaution/double check?

also, just to be clear, I don't have any herpes antibodies in my blood even though the index number is still <0.9, and this means I don't have HSV 1 or 2 at all?

Thank you so much once again, and sorry to be redundant, I just want to be perfectly clear.
Answered by Dr. Kakkar S. 1 hour later
Brief Answer:
No need to re-test

Detailed Answer:

I don't think there is a need to test at 6 months.
Yes, you don't have any antibodies against the virus because you don't have the infection. If you were infected you would have had circulating IgG antibodies by now.
Index value 'less than 0.9' indicates that you don't have antibodies.

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar

The User accepted the expert's answer

Share on
Question is related to
Medical Topics ,   ,  

Recent questions on  Hsv

doctor1 MD

Yes, thank you. My daughter was tested ( blood) and was told she has Herpes Simplex 2. What is it, how did she get it, what do we do now?

doctor1 MD

Hi, please need your help on this to get clarified. 1) I had protected intercourse with 4 sex workers. I didn't find any breakage in condom in all occasions. 2) I did kissing (not deep, not even with tongue) 3) fingered in the girls vagina (as far...

doctor1 MD

I have a globus sensation for 3 months now with dizziness . My doctor said that it is just due to my allergies causing post nasal drip leading to said sensation. However, I have noticed these lesions in the back of my throat and now I am wondering...

doctor1 MD


I am a 26-year old female who has just been diagnosed with HSV 2. I have been with my husband for 5 years and this is the first time I have experienced symptoms. He has never experienced symptoms. We have both been faithful. We have had unprotected sex for 5 years now. We have also both had previous partners before eachother. How likely is it that he also has HSV 2? Thank you.

doctor1 MD

Hello, ive been with my current girlfriend for two months now. She had only been with one other guy before me and has never had a problem until me. She went for std testing after she experienced discomfort and was diagnosed with hsv 2. So the following week I went to a physician and was tested and i tested positive for hsv 1 but not hsv 2. How is this possible