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Is Klonopin A Short Acting Drug?
Question: Hi,
I am on Klonopin 3 mg (and soon 4 mg), Lexapro 5 mg, Keppra 1000 mg and Amisulpride (Solian) 100mg.
I am fighting with an "ocd like symptom" ("ocd like", because without rituals and son on) probably probably created by Solian at low dosage, since it's proven (i've been told it here) that Amisulpride 100 mg can have dopaminergic activity and (also told here) can create this kind of symptom.
I had the same problem in 2009, but i was before on Lamictal and (attention please) Klonopin 3 mg (not 1 mg) for many years. Once in 2009 my psychiatrist decided to try Keppra instead of Lamictal, this "ocd like" symptom disappeared (completely, 100 %) during many years. But it happens that since three years ago i was on Klonopin 1 mg and my psychiatrist decided to go back to Keppra (i was taking a biosimilar which is no more avalaible in the market), but mantaining first Klonopin 1 mg and then just 2 mg. There was some good effect witk Keppra, but there still was this "ocd like symptom". I've been told here that Klonopin can help to fight dopaminergic activity (and it seems that more Klonopin helps), so i would like to know if now that my psychiatrist decided to go back to Klonopin 3 mg it can help to resolve my situation, since i am back to the situation when in 2009 this symptom disappeared. I would like to know if this is possible soon and if i have to wait some time to have the benefits of cumulative effects o.Klonopin.
I received here in this site a wrong information (saying that Klonopin is a "short acting drug") and also the following link from another doctor (aslso here):
http://www.medsafe.govt.nz/profs/datasheet/p/Paxamtab.pdf
I hope to receive a true information since sometimes i receive contradictory explanations and maybe in this case the origin is a mistake in dose choosen by my psychiatrist to fight my symptom.
Please, i don't need "to feel relax" and i don't need this kind of "coaching" i am here to receive as far as possible information close to real effects of meds.
Best regards, XXXXXXX
I am on Klonopin 3 mg (and soon 4 mg), Lexapro 5 mg, Keppra 1000 mg and Amisulpride (Solian) 100mg.
I am fighting with an "ocd like symptom" ("ocd like", because without rituals and son on) probably probably created by Solian at low dosage, since it's proven (i've been told it here) that Amisulpride 100 mg can have dopaminergic activity and (also told here) can create this kind of symptom.
I had the same problem in 2009, but i was before on Lamictal and (attention please) Klonopin 3 mg (not 1 mg) for many years. Once in 2009 my psychiatrist decided to try Keppra instead of Lamictal, this "ocd like" symptom disappeared (completely, 100 %) during many years. But it happens that since three years ago i was on Klonopin 1 mg and my psychiatrist decided to go back to Keppra (i was taking a biosimilar which is no more avalaible in the market), but mantaining first Klonopin 1 mg and then just 2 mg. There was some good effect witk Keppra, but there still was this "ocd like symptom". I've been told here that Klonopin can help to fight dopaminergic activity (and it seems that more Klonopin helps), so i would like to know if now that my psychiatrist decided to go back to Klonopin 3 mg it can help to resolve my situation, since i am back to the situation when in 2009 this symptom disappeared. I would like to know if this is possible soon and if i have to wait some time to have the benefits of cumulative effects o.Klonopin.
I received here in this site a wrong information (saying that Klonopin is a "short acting drug") and also the following link from another doctor (aslso here):
http://www.medsafe.govt.nz/profs/datasheet/p/Paxamtab.pdf
I hope to receive a true information since sometimes i receive contradictory explanations and maybe in this case the origin is a mistake in dose choosen by my psychiatrist to fight my symptom.
Please, i don't need "to feel relax" and i don't need this kind of "coaching" i am here to receive as far as possible information close to real effects of meds.
Best regards, XXXXXXX
Brief Answer:
Higher doses will have better effects
Detailed Answer:
Hello, Welcome to Health Care Magic
Hello again XXXXXXX first of all I'd like to apologise to you for the confusion created due to some wrong information given by me. I have mentioned that the drug is short acting but what I meant was that the drug is rapid acting which means the drugs shows rapid effects. Clonazepam is a long acting benzodiazepine drug and if we consider half life of the drug then it's about 20-45 hours. The drug acts quickly and long acting and this is the reason the drug is used in a number of disorders and have wide therapeutic range.
Now coming to its cumulative effects. Though it's not a typical cumulation of effects but higher doses would result in high concentration in brain and this will result in more and more plasma protein binding. Increased doses this will result in additive or cumulative effects so high efficacy. So increasing the dose in your case will help in better symptom control over time. Wait for some time and you will again see total improvement.
The drug in some recent studies is also found to have antidopaminergic effects and this is the probable reason the drug will help to fight the OC like symptoms. Higher doses have more effects so increasing the dose will help in better control.
Thanks, Hope this helps you, if you have more doubts you can ask again. I have used some technical terms just to help you in understanding and if you want to clear some thing please don't hesitate to ask in follow up.
Higher doses will have better effects
Detailed Answer:
Hello, Welcome to Health Care Magic
Hello again XXXXXXX first of all I'd like to apologise to you for the confusion created due to some wrong information given by me. I have mentioned that the drug is short acting but what I meant was that the drug is rapid acting which means the drugs shows rapid effects. Clonazepam is a long acting benzodiazepine drug and if we consider half life of the drug then it's about 20-45 hours. The drug acts quickly and long acting and this is the reason the drug is used in a number of disorders and have wide therapeutic range.
Now coming to its cumulative effects. Though it's not a typical cumulation of effects but higher doses would result in high concentration in brain and this will result in more and more plasma protein binding. Increased doses this will result in additive or cumulative effects so high efficacy. So increasing the dose in your case will help in better symptom control over time. Wait for some time and you will again see total improvement.
The drug in some recent studies is also found to have antidopaminergic effects and this is the probable reason the drug will help to fight the OC like symptoms. Higher doses have more effects so increasing the dose will help in better control.
Thanks, Hope this helps you, if you have more doubts you can ask again. I have used some technical terms just to help you in understanding and if you want to clear some thing please don't hesitate to ask in follow up.
Note: For further guidance on mental health, Click here.
Above answer was peer-reviewed by :
Dr. Chakravarthy Mazumdar
Answered by
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