Hi i have been taking prednisone 2.5 mg once a
Hello and welcome,
A dose of 2.5 mg is low, but the duration may have been enough to suppress your adrenal axis. The adrenal glands produce cortisol in response to stress, and they produce at least some everyday. If a steroid is present in the form of medication (such as prednisone), it tells the pituitary gland that you have enough, and the pituitary tells the adrenal glands not to make more. Then, when the outside source stops (ie you stope taking prednisone), it takes a while for that suppression to stop and for the adrenal glands to kick back in and make the appropriate amount.
Usually we see this suppression at higher doses, but it can happen at any dose really, and the longer a person is on, the more likely. So while 5 days on prednisone may not cause it, being on more than 10-14 days can.
The trick will be to taper even more slowly. Try taking 1/2 tablets (if you have 2.5 mg tablets) and try to take it around 8 am if you can, to simulate the natural diurnal rhythm of cortisol release. But before doing this, talk with your doctor so that the two of you do this together. I don't know the reason you were taking the prednisone, so I want to be cautious about just telling you what to do here without your doctor's input. The duration for which to take the 1/2 tablet isn't set in stone by guidelines, but you may need to do it for a couple of weeks.
I hope this information helps.
Thoughts on this
It may be that on the 1/2 tablet (ie 1.25 mg) that your body will start recognizing the need for making more cortisol. However, I don't know the reason you are taking prednisone, and if it has to do with Addison's disease or other adrenal problems, then you may need to continue to take it and I would not recommend quitting without discussing with your endocrinologist.
It may be hard to quarter the small tablets. If after the 2 weeks on 1/2 tablet, you find you are having problem without any, then consider talking with the endocrinologist about the difficulty you are having. He/she may want to give you 1 mg tabs which can be cut in half. But you may be feeling better by then.