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Hello Everyone. Its Been Sometime Since I Last Posted. Developed
Question: Hello everyone. Its been sometime since I last posted. Developed a rejection. I am alsmost 2.5 years post LTX. Since rejection I have been put on 20 mg prednisolone for some time now and my doc wants me to be on this long term as I am responding well to it BUT i have started developing the horrible side effects of this drug such as elevated blood sugar, high cholesterol, overweight BMI! How can I prevent these from getting worse and even reversing?
NOTE: my transplant doc is not interested in dealing with these at the moment and he seems not to be bothered by these BUT i do not want to face a point of no return situation!
Thanks!
NOTE: my transplant doc is not interested in dealing with these at the moment and he seems not to be bothered by these BUT i do not want to face a point of no return situation!
Thanks!
Hello everyone. Its been sometime since I last posted. Developed a rejection. I am alsmost 2.5 years post LTX. Since rejection I have been put on 20 mg prednisolone for some time now and my doc wants me to be on this long term as I am responding well to it BUT i have started developing the horrible side effects of this drug such as elevated blood sugar, high cholesterol, overweight BMI! How can I prevent these from getting worse and even reversing?
NOTE: my transplant doc is not interested in dealing with these at the moment and he seems not to be bothered by these BUT i do not want to face a point of no return situation!
Thanks!
NOTE: my transplant doc is not interested in dealing with these at the moment and he seems not to be bothered by these BUT i do not want to face a point of no return situation!
Thanks!
Brief Answer:
The therapy of Liver transplant is more important.
Detailed Answer:
Hi
I have gone through your query and here is my opinion.
It is true that high dosis or long term tharapy with prednisolone can trigger Diabetes , Hypertension,Dyslipidemia and produce weight gain.
Long-term use of glucocorticoids can also result in Cushing's syndrome, which can lead to: a fatty hump between your shoulders.
These effects are more probable in high dosis+ long term therapy with glucocorticoids.(like in your case)
Anyway the good news is that these effect of steroids are usually transient and reversible.
As steroid doses are reduced, their effect on endocrine metabolism returns to baseline and drug-induced diabetes is expected to resolve; however, this is not true in all cases.
The LTx is more important for you in this moment.
Anyway,Don't worry because all thse side effects will gradually disappear when your prednisolone dosis will be reduced,( this is more probable when you will stop taking this drug)
Hope this is helpful.
Regards
The therapy of Liver transplant is more important.
Detailed Answer:
Hi
I have gone through your query and here is my opinion.
It is true that high dosis or long term tharapy with prednisolone can trigger Diabetes , Hypertension,Dyslipidemia and produce weight gain.
Long-term use of glucocorticoids can also result in Cushing's syndrome, which can lead to: a fatty hump between your shoulders.
These effects are more probable in high dosis+ long term therapy with glucocorticoids.(like in your case)
Anyway the good news is that these effect of steroids are usually transient and reversible.
As steroid doses are reduced, their effect on endocrine metabolism returns to baseline and drug-induced diabetes is expected to resolve; however, this is not true in all cases.
The LTx is more important for you in this moment.
Anyway,Don't worry because all thse side effects will gradually disappear when your prednisolone dosis will be reduced,( this is more probable when you will stop taking this drug)
Hope this is helpful.
Regards
Above answer was peer-reviewed by :
Dr. Yogesh D
Brief Answer:
The therapy of Liver transplant is more important.
Detailed Answer:
Hi
I have gone through your query and here is my opinion.
It is true that high dosis or long term tharapy with prednisolone can trigger Diabetes , Hypertension,Dyslipidemia and produce weight gain.
Long-term use of glucocorticoids can also result in Cushing's syndrome, which can lead to: a fatty hump between your shoulders.
These effects are more probable in high dosis+ long term therapy with glucocorticoids.(like in your case)
Anyway the good news is that these effect of steroids are usually transient and reversible.
As steroid doses are reduced, their effect on endocrine metabolism returns to baseline and drug-induced diabetes is expected to resolve; however, this is not true in all cases.
The LTx is more important for you in this moment.
Anyway,Don't worry because all thse side effects will gradually disappear when your prednisolone dosis will be reduced,( this is more probable when you will stop taking this drug)
Hope this is helpful.
Regards
The therapy of Liver transplant is more important.
Detailed Answer:
Hi
I have gone through your query and here is my opinion.
It is true that high dosis or long term tharapy with prednisolone can trigger Diabetes , Hypertension,Dyslipidemia and produce weight gain.
Long-term use of glucocorticoids can also result in Cushing's syndrome, which can lead to: a fatty hump between your shoulders.
These effects are more probable in high dosis+ long term therapy with glucocorticoids.(like in your case)
Anyway the good news is that these effect of steroids are usually transient and reversible.
As steroid doses are reduced, their effect on endocrine metabolism returns to baseline and drug-induced diabetes is expected to resolve; however, this is not true in all cases.
The LTx is more important for you in this moment.
Anyway,Don't worry because all thse side effects will gradually disappear when your prednisolone dosis will be reduced,( this is more probable when you will stop taking this drug)
Hope this is helpful.
Regards
Note: For more information on hormonal imbalance symptoms or unmanaged diabetes with other comorbid conditions, get back to us & Consult with an Endocrinologist. Click here to book an appointment.
Above answer was peer-reviewed by :
Dr. Yogesh D
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