HealthCareMagic is now Ask A Doctor - 24x7 | https://www.askadoctor24x7.com

question-icon

Hello ! I M Healthy Person - But In Understand

default
Posted on Fri, 25 Dec 2020
Question: Hello !
I m healthy person - but in understand that i too much thinking and reading makes you stress - so I need expert advice !
So avoid reading unnecessary - wont make stress in my mind

Acute disease can make your little bit CD4 cells go down

1. For example Acute C hepatitis - it could lower CD4 amount - but not so much in early stage (acute C hepatitis) that it could cause latent Tuberculosis activation ?
Of course C hepatitis should be treated that it dont cause any problem in future - just CURE C hepatitis early !

2. In healthy person any acute disease could lower little bit CD4 amount - but not so much as it could cause latent Tuberculosis activation !

And with proper treatment CD4 amount will go up and resolve all problems ?

I hope for positive answer that won make you stress but relax !

Thank you very much !

default
Follow up: Dr. Drkaushal85 (0 minute later)
Hello !
I m healthy person - but in understand that i too much thinking and reading makes you stress - so I need expert advice !
So avoid reading unnecessary - wont make stress in my mind

Acute disease can make your little bit CD4 cells go down

1. For example Acute C hepatitis - it could lower CD4 amount - but not so much in early stage (acute C hepatitis) that it could cause latent Tuberculosis activation ?
Of course C hepatitis should be treated that it dont cause any problem in future - just CURE C hepatitis early !

2. In healthy person any acute disease could lower little bit CD4 amount - but not so much as it could cause latent Tuberculosis activation !

And with proper treatment CD4 amount will go up and resolve all problems ?

I hope for positive answer that won make you stress but relax !

Thank you very much !

doctor
Answered by Dr. Drkaushal85 (4 hours later)
Brief Answer:
Yes, your assumptions are correct.

Detailed Answer:
Thanks for your question on Ask a doctor forum.
I can understand your concern.
Yes, your both assumptions are correct.
Any acute infection (viral or bacterial or fungal or parasitic) can cause reduction in CD4 count and this can ultimately lead to reactivation of latent Tuberculosis.
Hope I have solved your query. I will be happy to help you further. Wish you good health. Thanks.
Above answer was peer-reviewed by : Dr. Prasad
doctor
doctor
Answered by Dr. Drkaushal85 (0 minute later)
Brief Answer:
Yes, your assumptions are correct.

Detailed Answer:
Thanks for your question on Ask a doctor forum.
I can understand your concern.
Yes, your both assumptions are correct.
Any acute infection (viral or bacterial or fungal or parasitic) can cause reduction in CD4 count and this can ultimately lead to reactivation of latent Tuberculosis.
Hope I have solved your query. I will be happy to help you further. Wish you good health. Thanks.
Above answer was peer-reviewed by : Dr. Prasad
doctor
default
Follow up: Dr. Drkaushal85 (2 hours later)
you did dont call me down !!

you made me more stress - my question is more that it could not activate latent tuberculosis
XXXXXXX it could activate -

just imagine if i get some bacterial infection - but otherwise i m healthy will i get activization of my tuberculosis

no - then every one who has latent tuberculosis would activate it -

But we dont see it

for example acute HCV increase CD4 amount it is showed in this publication

you can see in diagramma imige

https://www.sciencedirect.com/science/article/pii/S0000

- answer acute HCV increase CD4 - and dont increase risk for tuberculosis activation !!!


and very important information that prove that only mild CD4 decrease and then it goes up after recovery !

Certain viral and bacterial infections have correlations with a mild decrease in CD4 cell count. These have been documented in viral infections such as Ebstein Barr Virus (EBV), cytomegalovirus (CMV)

https://www.ncbi.nlm.nih.gov/books/NBK470231/



And cd4 in HCV decrease in late stage but in early stage it up - and if it is early cure there is no problems to immunity and health

Patients with Hepatitis C virus (HCV) cirrhosis tend to have lower CD4 cell counts

https://www.ncbi.nlm.nih.gov/books/NBK470231/


your answer made me more stressful - and made me search for information by my own

so i could calm down me by myself




default
Follow up: Dr. Drkaushal85 (0 minute later)
you did dont call me down !!

you made me more stress - my question is more that it could not activate latent tuberculosis
XXXXXXX it could activate -

just imagine if i get some bacterial infection - but otherwise i m healthy will i get activization of my tuberculosis

no - then every one who has latent tuberculosis would activate it -

But we dont see it

for example acute HCV increase CD4 amount it is showed in this publication

you can see in diagramma imige

https://www.sciencedirect.com/science/article/pii/S0000

- answer acute HCV increase CD4 - and dont increase risk for tuberculosis activation !!!


and very important information that prove that only mild CD4 decrease and then it goes up after recovery !

Certain viral and bacterial infections have correlations with a mild decrease in CD4 cell count. These have been documented in viral infections such as Ebstein Barr Virus (EBV), cytomegalovirus (CMV)

https://www.ncbi.nlm.nih.gov/books/NBK470231/



And cd4 in HCV decrease in late stage but in early stage it up - and if it is early cure there is no problems to immunity and health

Patients with Hepatitis C virus (HCV) cirrhosis tend to have lower CD4 cell counts

https://www.ncbi.nlm.nih.gov/books/NBK470231/


your answer made me more stressful - and made me search for information by my own

so i could calm down me by myself




doctor
Answered by Dr. Drkaushal85 (20 hours later)
Brief Answer:
But, it is not true always.

Detailed Answer:
Thanks for your follow up question on the Ask a doctor forum.

First of all, sorry for the late reply as I was busy.
And it is not always True.
Not always, low CD4 count due to acute infection causes reactivation of Tuberculosis.
This also depends on the duration and severity of the infection.

Hope I have solved your query.
I will be happy to help you further.
Wish you good health.
Thanks.


Above answer was peer-reviewed by : Dr. Arnab Banerjee
doctor
doctor
Answered by Dr. Drkaushal85 (0 minute later)
Brief Answer:
But, it is not true always.

Detailed Answer:
Thanks for your follow up question on the Ask a doctor forum.

First of all, sorry for the late reply as I was busy.
And it is not always True.
Not always, low CD4 count due to acute infection causes reactivation of Tuberculosis.
This also depends on the duration and severity of the infection.

Hope I have solved your query.
I will be happy to help you further.
Wish you good health.
Thanks.


Above answer was peer-reviewed by : Dr. Arnab Banerjee
doctor
default
Follow up: Dr. Drkaushal85 (5 hours later)
Hello

to end up this discussion and stop it is summery

Those who have poor health condition has risk

For example HIV + you get some infection that lower more CD4 and immunity you could get active Tuberculosis

But for healthy person how get some infection that lower little bit CD4 and immunity there is no risk for active Tuberculosis

As in all info said that risk group is persons with health condition - no healthy person who get some light infection

Please say shot yes that I m right - and end up this discussion

From CDC page
https://www.cdc.gov/tb/topic/basics/risk.htm

Persons with Medical Conditions that Weaken the Immune System
Babies and young children often have weak immune systems. Other people can have weak immune systems, too, especially people with any of these conditions:

HIV infe
ction (the virus that causes AIDS)
Substance abuse
Silicosis
Diabetes mellitus
Severe kidney disease
Low body weight
Organ transplants
Head and neck cancer
Medical treatments such as corticosteroids or organ transplant
Specialized treatment for rheumatoid arthritis or Crohn’s disease




default
Follow up: Dr. Drkaushal85 (0 minute later)
Hello

to end up this discussion and stop it is summery

Those who have poor health condition has risk

For example HIV + you get some infection that lower more CD4 and immunity you could get active Tuberculosis

But for healthy person how get some infection that lower little bit CD4 and immunity there is no risk for active Tuberculosis

As in all info said that risk group is persons with health condition - no healthy person who get some light infection

Please say shot yes that I m right - and end up this discussion

From CDC page
https://www.cdc.gov/tb/topic/basics/risk.htm

Persons with Medical Conditions that Weaken the Immune System
Babies and young children often have weak immune systems. Other people can have weak immune systems, too, especially people with any of these conditions:

HIV infe
ction (the virus that causes AIDS)
Substance abuse
Silicosis
Diabetes mellitus
Severe kidney disease
Low body weight
Organ transplants
Head and neck cancer
Medical treatments such as corticosteroids or organ transplant
Specialized treatment for rheumatoid arthritis or Crohn’s disease




doctor
Answered by Dr. Drkaushal85 (1 hour later)
Brief Answer:
Yes, your understanding is correct.

Detailed Answer:
Thanks for your follow up question on Ask a doctor forum.
Yes, your understanding is correct.
Hope I have solved your query. If you are not having further queries, then please close the conversation and rate my answer. You can ask me directly on bit.ly/askdrkaushalbhavsar.
Wish you good health. Thanks.
Above answer was peer-reviewed by : Dr. Kampana
doctor
doctor
Answered by Dr. Drkaushal85 (0 minute later)
Brief Answer:
Yes, your understanding is correct.

Detailed Answer:
Thanks for your follow up question on Ask a doctor forum.
Yes, your understanding is correct.
Hope I have solved your query. If you are not having further queries, then please close the conversation and rate my answer. You can ask me directly on bit.ly/askdrkaushalbhavsar.
Wish you good health. Thanks.
Note: For further information on diet changes to reduce allergy symptoms or to boost your immunity, Ask here.

Above answer was peer-reviewed by : Dr. Kampana
doctor
Answered by
Dr.
Dr. Drkaushal85

Pulmonologist

Practicing since :2008

Answered : 15005 Questions

premium_optimized

The User accepted the expert's answer

Share on

Get personalised answers from verified doctor in minutes across 80+ specialties

159 Doctors Online

By proceeding, I accept the Terms and Conditions

HCM Blog Instant Access to Doctors
HCM Blog Questions Answered
HCM Blog Satisfaction
Hello ! I M Healthy Person - But In Understand

Hello ! I m healthy person - but in understand that i too much thinking and reading makes you stress - so I need expert advice ! So avoid reading unnecessary - wont make stress in my mind Acute disease can make your little bit CD4 cells go down 1. For example Acute C hepatitis - it could lower CD4 amount - but not so much in early stage (acute C hepatitis) that it could cause latent Tuberculosis activation ? Of course C hepatitis should be treated that it dont cause any problem in future - just CURE C hepatitis early ! 2. In healthy person any acute disease could lower little bit CD4 amount - but not so much as it could cause latent Tuberculosis activation ! And with proper treatment CD4 amount will go up and resolve all problems ? I hope for positive answer that won make you stress but relax ! Thank you very much !