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Have severe kidney, UTI infection and tested positive for hla-b27. What do you recommend?

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Posted on Mon, 2 Dec 2013
Question: For almost 3 years had a very low immune system. Several kidney and uti infections. My vitamin D is always low even with supplements. I have severe pain in my spine, upper neck, lower back., knees, wrists, front of foot. i tested positive for hla-b27. It's a gene, but I don't have any family history. Lately my legs from my knee up will swell with fluid so I keep my feet elevated to help. My insurance has expired and won't have any until the first of the year. My stress and anxiety is high even with medication.
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Answered by Dr. Shruti Rijhwani (5 hours later)
Brief Answer: Follows. Detailed Answer: Dear Madam, Thank you for posting your query on XXXXXXX Well looking into your problem it is possible that you are suffering from the condition known as seronegative spondyloarthropathy ( ankylosing spondylitis ) since you are HLA B 27 positive also . It seems that you have both axial as well as peripheral manifestation as you have pain in back along with swelling in joints . I will advise you to see a rheumatologist and get your disease activity assessed . You need to get a CBC , ESR , CRP , X Ray pelvis and possible MRI pelvis to look for sacroillitis . Only after assessment of your disease activity proper treatment will be initiated . Please do not ignore the problem . Physical examination is very important in this disease as various tests like schobers test , figure of 4 test is needed for disease assessment . So , seek medical advise as soon as possible . Take care. Dr. Shruti
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
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Answered by
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Dr. Shruti Rijhwani

Rheumatologist

Practicing since :2008

Answered : 2366 Questions

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Have severe kidney, UTI infection and tested positive for hla-b27. What do you recommend?

Brief Answer: Follows. Detailed Answer: Dear Madam, Thank you for posting your query on XXXXXXX Well looking into your problem it is possible that you are suffering from the condition known as seronegative spondyloarthropathy ( ankylosing spondylitis ) since you are HLA B 27 positive also . It seems that you have both axial as well as peripheral manifestation as you have pain in back along with swelling in joints . I will advise you to see a rheumatologist and get your disease activity assessed . You need to get a CBC , ESR , CRP , X Ray pelvis and possible MRI pelvis to look for sacroillitis . Only after assessment of your disease activity proper treatment will be initiated . Please do not ignore the problem . Physical examination is very important in this disease as various tests like schobers test , figure of 4 test is needed for disease assessment . So , seek medical advise as soon as possible . Take care. Dr. Shruti