Experiencing Pain All Over Body. Blood Test Normal. MRI Done. What Is The Disease Called?
Thank you for posting your query.
I can understand the discomfort your husband is facing on account of pain, and also as no definite diagnosis has yet been made for his symptoms.
As I can see, the main symptoms are pain in joints & muscles, along with weakness.
Regarding the diagnosis of rheumatoid arthritis, if the blood tests are negative, it could be seronegative rheumatoid arthritis (RA). But I do not think the clinical picture is like RA. In RA, mainly small joints of hands & feet are affected, with swelling, and morning stiffness.
I presume serum Uric acid is normal, as high Uric acid can also lead to joint pains.
The most likely diagnosis could be fibromyalgia. In this condition, there are multiple areas of pains, including neck, back, hamstrings, etc. These areas are tender on applying pressure.
Regarding weakness, I hope a nerve conduction studies (NCV) and EMG have been done. This can help in determining if he has a neuropathy (nerve disease) or muscle disease. A blood test CPK can also help in finding out a muscle disease.
A deficiency of vitamin B12 can contribute to the weakness, so, it is worthwhile checking serum vitamin B12 levels, if not checked.
Regarding the MRI brain finding, it is not a specific finding. The most common condition where this can occur is migraine. However, in your husband's case, it is an incidental finding, and as of now, it can be ignored.
I hope it helps. Please get back, if you have any more queries.
Best wishes,
Dr Sudhir Kumar MD DM (Neurology) XXXXXXX Consultant Neurologist