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Dear Doctor, My Mom Had Several Times Of Stomach Ache,
Question: Dear doctor, my mom had several times of stomach ache, from endoscopy clean and colonoscopy there were some polip but its stated that the polip is inflamation polip desendan colon rectum...the problem is tes faecal calprotectin is up and down sharply : 153.8, 8.6, 341.1, 26.7, 197.8, 50.2 and 414.7. M2pk test is normal. From colonoscopy my mother also has hemorroid My mother also has sjogren My mother is on medication: myfortic, budenofalk and salofalk. Please suggest... Also the up level of calprotectin can be cause by hemorrhoids?
Dear doctor, my mom had several times of stomach ache, from endoscopy clean and colonoscopy there were some polip but its stated that the polip is inflamation polip desendan colon rectum...the problem is tes faecal calprotectin is up and down sharply : 153.8, 8.6, 341.1, 26.7, 197.8, 50.2 and 414.7. M2pk test is normal. From colonoscopy my mother also has hemorroid My mother also has sjogren My mother is on medication: myfortic, budenofalk and salofalk. Please suggest... Also the up level of calprotectin can be cause by hemorrhoids?
Brief Answer:
Please go through detailed answer.
Detailed Answer:
Hello and thanks for choosing "Ask a Doctor" service for your query,
Have gone through your details,
Inflammation any where along the lining of gut would cause elevated levels of serum calprotectin.
Calprotectin is infact a marker of inflammation.
This rapid rise is due to polyp.Was a biopsy sample taken is the polyp benign or malignant?
Why was it surgically not taken out?
As the polyp size is increasing so does the inflammation therefore serum calprotectin is done.
First suggestion is biopsy of polyp should be done to see if they are non cancerous or cancerous.Usually multiple and polyp larger then 10 mm are cancerous.
Secondly hemorrhoids have nothing to do with calprotectin levels.
In case you need any other suggestion do feel free to ask,
Hope i was helpful,
Thank you!
Please go through detailed answer.
Detailed Answer:
Hello and thanks for choosing "Ask a Doctor" service for your query,
Have gone through your details,
Inflammation any where along the lining of gut would cause elevated levels of serum calprotectin.
Calprotectin is infact a marker of inflammation.
This rapid rise is due to polyp.Was a biopsy sample taken is the polyp benign or malignant?
Why was it surgically not taken out?
As the polyp size is increasing so does the inflammation therefore serum calprotectin is done.
First suggestion is biopsy of polyp should be done to see if they are non cancerous or cancerous.Usually multiple and polyp larger then 10 mm are cancerous.
Secondly hemorrhoids have nothing to do with calprotectin levels.
In case you need any other suggestion do feel free to ask,
Hope i was helpful,
Thank you!
Above answer was peer-reviewed by :
Dr. Yogesh D
Brief Answer:
Please go through detailed answer.
Detailed Answer:
Hello and thanks for choosing "Ask a Doctor" service for your query,
Have gone through your details,
Inflammation any where along the lining of gut would cause elevated levels of serum calprotectin.
Calprotectin is infact a marker of inflammation.
This rapid rise is due to polyp.Was a biopsy sample taken is the polyp benign or malignant?
Why was it surgically not taken out?
As the polyp size is increasing so does the inflammation therefore serum calprotectin is done.
First suggestion is biopsy of polyp should be done to see if they are non cancerous or cancerous.Usually multiple and polyp larger then 10 mm are cancerous.
Secondly hemorrhoids have nothing to do with calprotectin levels.
In case you need any other suggestion do feel free to ask,
Hope i was helpful,
Thank you!
Please go through detailed answer.
Detailed Answer:
Hello and thanks for choosing "Ask a Doctor" service for your query,
Have gone through your details,
Inflammation any where along the lining of gut would cause elevated levels of serum calprotectin.
Calprotectin is infact a marker of inflammation.
This rapid rise is due to polyp.Was a biopsy sample taken is the polyp benign or malignant?
Why was it surgically not taken out?
As the polyp size is increasing so does the inflammation therefore serum calprotectin is done.
First suggestion is biopsy of polyp should be done to see if they are non cancerous or cancerous.Usually multiple and polyp larger then 10 mm are cancerous.
Secondly hemorrhoids have nothing to do with calprotectin levels.
In case you need any other suggestion do feel free to ask,
Hope i was helpful,
Thank you!
Above answer was peer-reviewed by :
Dr. Yogesh D
As per explained before the polip already taken out and it is benign.. The polip taken out by colonoscopy... And the up and down calprotectin also happening before and after that.
As per explained before the polip already taken out and it is benign.. The polip taken out by colonoscopy... And the up and down calprotectin also happening before and after that.
Brief Answer:
It's just a screening test much inferior to colonoscopy.
Detailed Answer:
Hi again
sorry I though the polyp is still there.
ok,Faecal calprotectin is a protein released by the white blood cells, neutrophils(defence cells), found in inflamed areas of the bowel in Inflammatory bowel disease specifically Crohn's disease and ulcerative coilitis. Its a screen test as every patient cannot be taken for colonoscopy.
So main purpose of FC in stool samples is to help distinguish Inflammatory Bowel Disease from other conditions(while screening patients).
So as said above,
Fecal Calprotectin is just an screening test and if polyp has already been removed then the only significance it has in your case is that there could be residual inflammation in intestines.
Give her some anti inflammatory medications with antacids eg ibuprofen and Prilosec twice daily for 1week and get the level checked up again.
Once the residual inflammation is gone levels would return back to normal.
Thank you.
It's just a screening test much inferior to colonoscopy.
Detailed Answer:
Hi again
sorry I though the polyp is still there.
ok,Faecal calprotectin is a protein released by the white blood cells, neutrophils(defence cells), found in inflamed areas of the bowel in Inflammatory bowel disease specifically Crohn's disease and ulcerative coilitis. Its a screen test as every patient cannot be taken for colonoscopy.
So main purpose of FC in stool samples is to help distinguish Inflammatory Bowel Disease from other conditions(while screening patients).
So as said above,
Fecal Calprotectin is just an screening test and if polyp has already been removed then the only significance it has in your case is that there could be residual inflammation in intestines.
Give her some anti inflammatory medications with antacids eg ibuprofen and Prilosec twice daily for 1week and get the level checked up again.
Once the residual inflammation is gone levels would return back to normal.
Thank you.
Above answer was peer-reviewed by :
Dr. Raju A.T
Brief Answer:
It's just a screening test much inferior to colonoscopy.
Detailed Answer:
Hi again
sorry I though the polyp is still there.
ok,Faecal calprotectin is a protein released by the white blood cells, neutrophils(defence cells), found in inflamed areas of the bowel in Inflammatory bowel disease specifically Crohn's disease and ulcerative coilitis. Its a screen test as every patient cannot be taken for colonoscopy.
So main purpose of FC in stool samples is to help distinguish Inflammatory Bowel Disease from other conditions(while screening patients).
So as said above,
Fecal Calprotectin is just an screening test and if polyp has already been removed then the only significance it has in your case is that there could be residual inflammation in intestines.
Give her some anti inflammatory medications with antacids eg ibuprofen and Prilosec twice daily for 1week and get the level checked up again.
Once the residual inflammation is gone levels would return back to normal.
Thank you.
It's just a screening test much inferior to colonoscopy.
Detailed Answer:
Hi again
sorry I though the polyp is still there.
ok,Faecal calprotectin is a protein released by the white blood cells, neutrophils(defence cells), found in inflamed areas of the bowel in Inflammatory bowel disease specifically Crohn's disease and ulcerative coilitis. Its a screen test as every patient cannot be taken for colonoscopy.
So main purpose of FC in stool samples is to help distinguish Inflammatory Bowel Disease from other conditions(while screening patients).
So as said above,
Fecal Calprotectin is just an screening test and if polyp has already been removed then the only significance it has in your case is that there could be residual inflammation in intestines.
Give her some anti inflammatory medications with antacids eg ibuprofen and Prilosec twice daily for 1week and get the level checked up again.
Once the residual inflammation is gone levels would return back to normal.
Thank you.
Above answer was peer-reviewed by :
Dr. Raju A.T
Dear doctor, as stated before... My mother still in medication myfortic, budenofalk and salofalk for months after the polip has been taken out... But the calprotectin level up and down 153 - 8-341-26-197-50-414
Dear doctor, as stated before... My mother still in medication myfortic, budenofalk and salofalk for months after the polip has been taken out... But the calprotectin level up and down 153 - 8-341-26-197-50-414
Brief Answer:
Follow up.
Detailed Answer:
Hello again my dear patient,
Sir what you have mentioned is the trade name of the medicines and I am unable to search them on google.In every country same salt is sold under varoius trade name.
please write the salt of each medicine mentioned by you and the doses and potency for eg taking paracetamol 500 mg twice daily so that I can get what she is on and from how long.
waiting!
Follow up.
Detailed Answer:
Hello again my dear patient,
Sir what you have mentioned is the trade name of the medicines and I am unable to search them on google.In every country same salt is sold under varoius trade name.
please write the salt of each medicine mentioned by you and the doses and potency for eg taking paracetamol 500 mg twice daily so that I can get what she is on and from how long.
waiting!
Above answer was peer-reviewed by :
Dr. Vaishalee Punj
Brief Answer:
Follow up.
Detailed Answer:
Hello again my dear patient,
Sir what you have mentioned is the trade name of the medicines and I am unable to search them on google.In every country same salt is sold under varoius trade name.
please write the salt of each medicine mentioned by you and the doses and potency for eg taking paracetamol 500 mg twice daily so that I can get what she is on and from how long.
waiting!
Follow up.
Detailed Answer:
Hello again my dear patient,
Sir what you have mentioned is the trade name of the medicines and I am unable to search them on google.In every country same salt is sold under varoius trade name.
please write the salt of each medicine mentioned by you and the doses and potency for eg taking paracetamol 500 mg twice daily so that I can get what she is on and from how long.
waiting!
Above answer was peer-reviewed by :
Dr. Vaishalee Punj
Mikofenolat or myfortic 180mg once daily, budenofalk or budesonide once daily and salofalk or mezalazine once daily
Mikofenolat or myfortic 180mg once daily, budenofalk or budesonide once daily and salofalk or mezalazine once daily
Brief Answer:
Follow up.
Detailed Answer:
Hello dear patient,
There is some thing grossly wrong in informations provided.
As per the information she only had a polyp while she is taking mezalazine which is specifically meant to treat inflammatory bowel disease either ulcerative coilitis or Crohn's disease.
Secondly she is on immunosuprrasant which is among one of the most toxic medicines.
Thirdly she is taking a steroidal anti inflammatory again used in inflammatory bowel disease.
As patient is having Inflammatory bowel disease and is on treatment fluctuations in level of Calprotectin is normal.
Sir this is not just a case of polyp she has some other diseases too.
Please provide to me all her medical records.
Follow up.
Detailed Answer:
Hello dear patient,
There is some thing grossly wrong in informations provided.
As per the information she only had a polyp while she is taking mezalazine which is specifically meant to treat inflammatory bowel disease either ulcerative coilitis or Crohn's disease.
Secondly she is on immunosuprrasant which is among one of the most toxic medicines.
Thirdly she is taking a steroidal anti inflammatory again used in inflammatory bowel disease.
As patient is having Inflammatory bowel disease and is on treatment fluctuations in level of Calprotectin is normal.
Sir this is not just a case of polyp she has some other diseases too.
Please provide to me all her medical records.
Above answer was peer-reviewed by :
Dr. Prasad
Brief Answer:
Follow up.
Detailed Answer:
Hello dear patient,
There is some thing grossly wrong in informations provided.
As per the information she only had a polyp while she is taking mezalazine which is specifically meant to treat inflammatory bowel disease either ulcerative coilitis or Crohn's disease.
Secondly she is on immunosuprrasant which is among one of the most toxic medicines.
Thirdly she is taking a steroidal anti inflammatory again used in inflammatory bowel disease.
As patient is having Inflammatory bowel disease and is on treatment fluctuations in level of Calprotectin is normal.
Sir this is not just a case of polyp she has some other diseases too.
Please provide to me all her medical records.
Follow up.
Detailed Answer:
Hello dear patient,
There is some thing grossly wrong in informations provided.
As per the information she only had a polyp while she is taking mezalazine which is specifically meant to treat inflammatory bowel disease either ulcerative coilitis or Crohn's disease.
Secondly she is on immunosuprrasant which is among one of the most toxic medicines.
Thirdly she is taking a steroidal anti inflammatory again used in inflammatory bowel disease.
As patient is having Inflammatory bowel disease and is on treatment fluctuations in level of Calprotectin is normal.
Sir this is not just a case of polyp she has some other diseases too.
Please provide to me all her medical records.
Above answer was peer-reviewed by :
Dr. Prasad
Her doctor told her that she has IBD.... Myfortic is a dangerous one right?.. Should we stop the medicine?
Her doctor told her that she has IBD.... Myfortic is a dangerous one right?.. Should we stop the medicine?
Dear doctor i have told the story in my first question... Because of stomach ache several times in a year than she had colonoscopy then the polip already taken out...then because of the high faecal calprotectin level so my mother on the medication as i stated before
Dear doctor i have told the story in my first question... Because of stomach ache several times in a year than she had colonoscopy then the polip already taken out...then because of the high faecal calprotectin level so my mother on the medication as i stated before
Brief Answer:
Follow up.
Detailed Answer:
Hello my dear,
I can very well understand your plight right now because as a non medical person understanding things are somewhat difficult.
But polyp is some thing completely different than from inflammatory bowel disease.IBD is a permanent condition of intestine and requires almost lifelong treatment.Its not curable but symptoms are almost controllable.
The treatment she is having is the standard one.Calprotectin would always fluctuate in a patient with IBS.
See our body has a defence/Immune system which contains neutrophils.In IBD these neutrophils numbers increases greatly in intestinal cells.They are the neutrophils which secrete large amount of Calprotectin.As neutrophils are first line defence system therefore immunosuppressant is given other wise the body immunity would harm itself.Secondly as there is permanent inflammation an anti inflammatory is given.
Yes off course these medicines have side effects but without then things would start worsening.
Only thing I would suggest is to give her an antacid along with these medicines.They are all strong medicines and cause gastritis a condition in which there is inflammation in walls of stomach and small intestine causing pains.
I would suggest you to add over the counter Omeprazole twice daily.
Aches would be there as I said condition is controllable but not curable.Dont stop any medicine on your own.
Add the over the counter antacid I suggested.
Don't panic.
Things would get better.I assure you.
Follow up with any other confusion you have I would be happy to help.
Thanks!
Follow up.
Detailed Answer:
Hello my dear,
I can very well understand your plight right now because as a non medical person understanding things are somewhat difficult.
But polyp is some thing completely different than from inflammatory bowel disease.IBD is a permanent condition of intestine and requires almost lifelong treatment.Its not curable but symptoms are almost controllable.
The treatment she is having is the standard one.Calprotectin would always fluctuate in a patient with IBS.
See our body has a defence/Immune system which contains neutrophils.In IBD these neutrophils numbers increases greatly in intestinal cells.They are the neutrophils which secrete large amount of Calprotectin.As neutrophils are first line defence system therefore immunosuppressant is given other wise the body immunity would harm itself.Secondly as there is permanent inflammation an anti inflammatory is given.
Yes off course these medicines have side effects but without then things would start worsening.
Only thing I would suggest is to give her an antacid along with these medicines.They are all strong medicines and cause gastritis a condition in which there is inflammation in walls of stomach and small intestine causing pains.
I would suggest you to add over the counter Omeprazole twice daily.
Aches would be there as I said condition is controllable but not curable.Dont stop any medicine on your own.
Add the over the counter antacid I suggested.
Don't panic.
Things would get better.I assure you.
Follow up with any other confusion you have I would be happy to help.
Thanks!
Above answer was peer-reviewed by :
Dr. Nagamani Ng
Brief Answer:
Follow up.
Detailed Answer:
Hello my dear,
I can very well understand your plight right now because as a non medical person understanding things are somewhat difficult.
But polyp is some thing completely different than from inflammatory bowel disease.IBD is a permanent condition of intestine and requires almost lifelong treatment.Its not curable but symptoms are almost controllable.
The treatment she is having is the standard one.Calprotectin would always fluctuate in a patient with IBS.
See our body has a defence/Immune system which contains neutrophils.In IBD these neutrophils numbers increases greatly in intestinal cells.They are the neutrophils which secrete large amount of Calprotectin.As neutrophils are first line defence system therefore immunosuppressant is given other wise the body immunity would harm itself.Secondly as there is permanent inflammation an anti inflammatory is given.
Yes off course these medicines have side effects but without then things would start worsening.
Only thing I would suggest is to give her an antacid along with these medicines.They are all strong medicines and cause gastritis a condition in which there is inflammation in walls of stomach and small intestine causing pains.
I would suggest you to add over the counter Omeprazole twice daily.
Aches would be there as I said condition is controllable but not curable.Dont stop any medicine on your own.
Add the over the counter antacid I suggested.
Don't panic.
Things would get better.I assure you.
Follow up with any other confusion you have I would be happy to help.
Thanks!
Follow up.
Detailed Answer:
Hello my dear,
I can very well understand your plight right now because as a non medical person understanding things are somewhat difficult.
But polyp is some thing completely different than from inflammatory bowel disease.IBD is a permanent condition of intestine and requires almost lifelong treatment.Its not curable but symptoms are almost controllable.
The treatment she is having is the standard one.Calprotectin would always fluctuate in a patient with IBS.
See our body has a defence/Immune system which contains neutrophils.In IBD these neutrophils numbers increases greatly in intestinal cells.They are the neutrophils which secrete large amount of Calprotectin.As neutrophils are first line defence system therefore immunosuppressant is given other wise the body immunity would harm itself.Secondly as there is permanent inflammation an anti inflammatory is given.
Yes off course these medicines have side effects but without then things would start worsening.
Only thing I would suggest is to give her an antacid along with these medicines.They are all strong medicines and cause gastritis a condition in which there is inflammation in walls of stomach and small intestine causing pains.
I would suggest you to add over the counter Omeprazole twice daily.
Aches would be there as I said condition is controllable but not curable.Dont stop any medicine on your own.
Add the over the counter antacid I suggested.
Don't panic.
Things would get better.I assure you.
Follow up with any other confusion you have I would be happy to help.
Thanks!
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Above answer was peer-reviewed by :
Dr. Nagamani Ng
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