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Could Skin Inflammation Or Early Form Of Arthritis Cause High HS CRP Level?

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Posted on Tue, 29 Mar 2022
Question: My wife's GFR went down from around 28 or so to 14 at her last reading. We know of no major change in diet or meds or situation. She has been taking 5 mg of Melatonin at night to help her fall asleep. Could this Melatonin have any effect on her GFR?

all my wife's data, re: drugs, medications, medical history is on file. Advise if you don't have access to that data
doctor
Answered by Dr. salah saad shoman (19 hours later)
Brief Answer:
No

Detailed Answer:

Hello,

Melatonin is not reported to have that side effect on the kidney functions. However, the data was not attached to the query. So, please attach the data as a report attached to the query for me to asses and to be able to help you further.

Regards
Above answer was peer-reviewed by : Dr. Kampana
doctor
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Follow up: Dr. salah saad shoman (4 hours later)
DR Shoman My wife has been under a care of a Nephrologist for several years now. He monitors her BP and GFR. Her GFR has been running in the high 20s for several years but as noted it dropped to 14 the last test. He has prescribed Norvasc and she is taking Amiodarone for Afib Her BP is too low he said and the mode is systolic about 110. He upped her water intake to 80 oz a day. and reduced her Norvasc. She is on coumadin, Cilostazol, Crestor, Lopressor, Synthroid, and Calcitriol. .She had a third TKR a year ago because of a Strep Equine. Her knee still pains her but her infection is gone or subdued. Her Afib is under control and no problem. The only thing different from previous is her taking Melatonin but you and other DRS said there is no connection.
doctor
Answered by Dr. salah saad shoman (16 hours later)
Brief Answer:
Not related to medications

Detailed Answer:

Hi,

There are no reported interactions between the medications you have listed that can lead to such decrease in kidney functions. However several other causes can lead to such decrease including high blood glucose levels, high cholesterol or low calcium levels. I would recommend that you get a blood test to check on these levels and if found high treat accordingly. Also, an ultrasound or ct scan on the kidneys is indicated to help detect any possible dilatation, tumors or stones. You should note that such a decrease in the GFR levels is an indication that the kidneys are failing to perform their normal functions in detoxifying the blood. If this continues then you might need to schedule for dialysis.

I hope you find this helpful.
Note: For further queries related to kidney problems and comprehensive renal care, talk to a Nephrologist. Click here to Book a Consultation.

Above answer was peer-reviewed by : Dr. Kampana
doctor
Answered by
Dr.
Dr. salah saad shoman

Internal Medicine Specialist

Practicing since :2004

Answered : 3153 Questions

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Could Skin Inflammation Or Early Form Of Arthritis Cause High HS CRP Level?

Brief Answer: No Detailed Answer: Hello, Melatonin is not reported to have that side effect on the kidney functions. However, the data was not attached to the query. So, please attach the data as a report attached to the query for me to asses and to be able to help you further. Regards