Brief Answer: Can affect multiple joints simultaneously. Detailed Answer: Hello, Thanks for posting your query. Osteoarthritis is a generalized problem and affects all the bones of the body. The gradually increasing pain in the knees ankles wrists and neck with clicking and grinding sound are characteristic of the age related degenerative changes in your large joints. The progression of the disease can be monitored with the help of Bone mineral density test every 6 months. The treatment options include pain killers, hot fomentation, lubricating agents like glucosamine sulfate, chondroitin , dycerin, etc and some life style modifications and physiotherapy. Right now you can start taking Tablet Tylenol ( Acetaminophen) Double Strength after breakfast and after dinner. It is suggested to add calcium supplements 500mg each twice daily. This will take care of your mild symptoms in 3-5 days. You can start with walking and aerobic fitness exercises, quadriceps strengthening, patellar tapping, lateral heel wedges, etc- under the guidance of your physiotherapist. A Big No to Stair case, squatting postures, any chair which has a sitting platform lower than your knees. In severe cases intra articular injections of steroids and hyaluronic acid may be needed after consultation with your orthopaedician. I also encourage you to consult an orthopedician for physical examination. A few blood tests, CT / MRI scans of the affected joints will help us diagnose the condition and help us in choosing the best approach of treatment. I hope this answers your query. In case you have additional questions or doubts, you can forward them to me, and I shall be glad to help you out. Wishing you good health. Regards. Dr. Praveen Tayal. For future query, you can directly approach me through my profile URL http://bit.ly/Dr-Praveen-Tayal

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