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Can I Have Risperidone Along With Doxazone?

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Posted on Wed, 15 Oct 2014
Question: I am 82 years old. recently prescribed Risperidone 0.25mg . for halucinations at night.
I take doxazone 4mg every night which causes some dizzyness when I get out of bed.
will Risperidone increase dizzyness ? I also take 3 meds for high blood pressure.
Prescription info advises caution. I also have diabetes. I haven't taken Risperidone yet
I am afraid of problems. Please advise. XXXXXXX
doctor
Answered by Dr. Prakash H Muddegowda (34 minutes later)
Brief Answer:
Need not start Risperidone now.

Detailed Answer:
Hi,
Thanks for asking.
I am Dr. Prakash HM and I will be answering your query.

Looking at the clinical details and query, my opinion is as follows:

1. Orthostatic hypotension or blood pressure variation with position leading to dizziness is common in both doxazone and risperidone.

2. Additionally Risperidone can enhance the effect of anti-hypertensives.

3. However, if hallucination symptoms are present, you need to take medications. If you do not have as you have mentioned, not to worry for now.

Also, as you have not started Risperidone, you can wait and watch. If symptoms of hallucination starts, then you need to discuss with your doctor regarding careful titration of dose of anti-hypertensives and doxazone, so that excessive hypotension does not occur.

Do not start Risperidone without a second consultation and drug adjustment as severe hypotension is more dangerous than hypertension.

4. Postural hypotension is common at this age and it is getting exacerbated with doxazone. Make sure your movements are slow as any fall could be dangerous at this age.

Hope this helps.

Any further queries, happy to help again.

Dr. Prakash HM
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
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Follow up: Dr. Prakash H Muddegowda (2 days later)
I talked to my doctor about taking Risperidone. He suggested that I take
the tablets for about a week. The dose is only a quarter of a millagram.
If after a week I feel OK to continue taking Risperidone.
I still have not started taking Risperidone because I am afraid of new
medications. Can this small dose give me a problem ?
doctor
Answered by Dr. Prakash H Muddegowda (45 minutes later)
Brief Answer:
Yes, it can. Take precautions

Detailed Answer:
Hi,
Thanks for asking again.

Yes, even the smallest dose can increase risk of further hypotension. However, if you need and want to start you need to take precautions.

1. Avoid sudden movements.
2. Changing positions should be slow.
3. If anytime dizziness is felt, sit or lie down
4. Avoid any fall at high costs.

You can take the small dose, but with caution.

Any further queries, happy to help again.

Dr. Prakash HM
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
Answered by
Dr.
Dr. Prakash H Muddegowda

Geriatrics Specialist

Practicing since :2004

Answered : 2138 Questions

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Can I Have Risperidone Along With Doxazone?

Brief Answer: Need not start Risperidone now. Detailed Answer: Hi, Thanks for asking. I am Dr. Prakash HM and I will be answering your query. Looking at the clinical details and query, my opinion is as follows: 1. Orthostatic hypotension or blood pressure variation with position leading to dizziness is common in both doxazone and risperidone. 2. Additionally Risperidone can enhance the effect of anti-hypertensives. 3. However, if hallucination symptoms are present, you need to take medications. If you do not have as you have mentioned, not to worry for now. Also, as you have not started Risperidone, you can wait and watch. If symptoms of hallucination starts, then you need to discuss with your doctor regarding careful titration of dose of anti-hypertensives and doxazone, so that excessive hypotension does not occur. Do not start Risperidone without a second consultation and drug adjustment as severe hypotension is more dangerous than hypertension. 4. Postural hypotension is common at this age and it is getting exacerbated with doxazone. Make sure your movements are slow as any fall could be dangerous at this age. Hope this helps. Any further queries, happy to help again. Dr. Prakash HM