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Can Linzess Cause A Reduction In Urine Output Volume?

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Posted on Tue, 30 Jun 2015
Question: Can Linzess cause a reduction in urine volume output?
doctor
Answered by Dr. Panagiotis Zografakis (24 minutes later)
Brief Answer:
normally no

Detailed Answer:
Hello,

linzess is supposed to increase the water content of the stool in order to make it softer and easier to be expelled by the intestine. It won't cause a reduction in urine volume, at least not directly. Since it may induce diarrhea (and water loss) if the water is not adequately replenished and has caused dehydration then the urine volume may be reduced.

Symptoms that may indicate dehydration include thirst, orthostatic hypotension, a faster than normal heart rate, reduced skin elasticity etc

It's hard to reach this point of dehydration with such drugs though!

I hope you find my comments helpful!
You can contact me again, if you'd like any clarification or further information.

Kind Regards!
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
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Follow up: Dr. Panagiotis Zografakis (5 minutes later)
Maybe im being a little bit hypochondriacal, it just seems that my urine output is down to a daily average of about 750 ml +- which i think is in the normal range. I'll speak with my PCP on Monday. Thank you.
doctor
Answered by Dr. Panagiotis Zografakis (3 minutes later)
Brief Answer:
750 is low normal

Detailed Answer:
750ml is a low-normal value. If your urine is always dark yellow then perhaps you'd require more water. The darker the color, the worse the dehydration. Producing 750mL or urine effectively excludes the dehydration scenario I've been talking about in my previous answer!

Best wishes!
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
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Follow up: Dr. Panagiotis Zografakis (6 minutes later)
Urine is straw colored. Volume is quite low at night, but after coffee etc in the AM is about 60 ml per hour. Perhaps, I'm just not taking in enough fluids. Thanks.
doctor
Answered by Dr. Panagiotis Zografakis (20 minutes later)
Brief Answer:
Yes, more fluids will help - unless contraindicated

Detailed Answer:
You're welcome. Whatever is more than 30ml/h is OK but still low. 750/24=31.25. It won't do any harm to your kidneys but it's better if you get more fluids - unless you've got other medical conditions that may get worse with fluids like heart failure for example.
Note: For further follow up on related General & Family Physician Click here.

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
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Answered by
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Dr. Panagiotis Zografakis

Internal Medicine Specialist

Practicing since :1999

Answered : 3809 Questions

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Can Linzess Cause A Reduction In Urine Output Volume?

Brief Answer: normally no Detailed Answer: Hello, linzess is supposed to increase the water content of the stool in order to make it softer and easier to be expelled by the intestine. It won't cause a reduction in urine volume, at least not directly. Since it may induce diarrhea (and water loss) if the water is not adequately replenished and has caused dehydration then the urine volume may be reduced. Symptoms that may indicate dehydration include thirst, orthostatic hypotension, a faster than normal heart rate, reduced skin elasticity etc It's hard to reach this point of dehydration with such drugs though! I hope you find my comments helpful! You can contact me again, if you'd like any clarification or further information. Kind Regards!