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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Taking Akruit For TB. High SGPT And SGOT Levels. Reason?

hi
I am on akurit-4 (4 tabs in morning all together- after a light snack... as advised by a TB specialist in Govt Hospital Delhi)
Its been 1 month and my SGOT 112 and SGPT levels are 151.
cholesterol in the beginning of month was 314 and i reduced it to 203 by abstaining from oily food and cutting fried diet to almost nil.
I am only worried about raised OT PT levels, bilirubin is below 1...
please advise
Thanks
Wed, 8 May 2013
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Internal Medicine Specialist 's  Response
hi
as you are a patient of TB and taking anti TB course which are famous for drug induced hepatitis, but first you should know the following things:
anti tb course is very important to continue as resistance is very strong and then if we stop the att , response is little changed.
so tb drugs causes hepatitis or cholestatic hepatitis(increased bilirubin)
as your bilirubin is normal following are the drugs in priority to cause hepatitis
1.pza
2.inh
3.rif
so akurit has all the above ingrdients
if you dont feel pain in upper part of abdomen and nause or vomiting , and suggest 1 weekly LFTs , to see your alt and alp
if the abobe symptoms are there stop akurit go to gastroenterologist for re introduction of akurit separately once your alt and alp are normal after stopping taking akurit.
take care
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Taking Akruit For TB. High SGPT And SGOT Levels. Reason?

hi as you are a patient of TB and taking anti TB course which are famous for drug induced hepatitis, but first you should know the following things: anti tb course is very important to continue as resistance is very strong and then if we stop the att , response is little changed. so tb drugs causes hepatitis or cholestatic hepatitis(increased bilirubin) as your bilirubin is normal following are the drugs in priority to cause hepatitis 1.pza 2.inh 3.rif so akurit has all the above ingrdients if you dont feel pain in upper part of abdomen and nause or vomiting , and suggest 1 weekly LFTs , to see your alt and alp if the abobe symptoms are there stop akurit go to gastroenterologist for re introduction of akurit separately once your alt and alp are normal after stopping taking akurit. take care