Hi, Yes, during the course of treatment clindamycin can cause diarrhea apparently due to destruction of normal good bacteria and overgrowth of bad or harmful bacteria such as clostridium difficile. However, this antibiotic induced diarrhea usually subsides over few days after stopping the medicine. Based on the history you seem to have infective gastroenteritis for which I advise you to consult your doctor for proper evaluation and treatment which may involve antibiotics in addition to probiotics and correction of dehydration if any. Take care. Hope I have answered your question. Let me know if I can assist you further. Regards, Dr. Mohammed Taher Ali, General & Family Physician