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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Is It Safe To Have Clindamycin While Having Mononucleosis?

Im a 20 year old male who has been fighting off a sore throat (found out a few days ago it is strep) for the past three weeks. They had prescribed me to Augmentin(Amoxacillin) for the past week, and i broke out in a nasty full-body rash because of it. Im told this is very common for people who have Mononucleosis, so I am awaiting results fro my blood work to determine if I do have Mono. They changed me over the Clindamycin just in case there is a bacterial cause to my throat, but I am skeptical to take it after the rash I was given from the Augmentin. Will Clindamycin cause the similar allergic reaction to Mono that Augmentin does?
Tue, 2 Jan 2024
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General & Family Physician 's  Response
Hi,

Clindamycin that is an antibacterial drug is administered for throat infections (including streptococcal infection). If penicillin or same group type medicine is ineffective, then clindamycin may be given. Clindamycin may also be given, if it is found to be effective against the causative infection by specific tests. Though, clindamycin is not effective against mononucleosis, as it is an viral infection and clindamycin is not anti-viral. Simple means like adequate fluids, proper rest, healthy diet may help in its early recovery.

OTC analgesics may help in fever, pain & sore throat. Still, some times streptococcal infection of throat & mononucleosis may be present simultaneously, hence in such cases, clindamycin may have its role. Definitely, clindamycin may also result in allergic symptoms in prone cases. Particularly, if one is suffering from membranous enterocolitis, ulcerative colitis or Crohn's disease, use of clindamycin is strictly contra-indicated.

Take care. Hope I have answered your question. Let me know if I can assist you further.

Regards,
Dr. Satnarain Bansal, General & Family Physician
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Is It Safe To Have Clindamycin While Having Mononucleosis?

Hi, Clindamycin that is an antibacterial drug is administered for throat infections (including streptococcal infection). If penicillin or same group type medicine is ineffective, then clindamycin may be given. Clindamycin may also be given, if it is found to be effective against the causative infection by specific tests. Though, clindamycin is not effective against mononucleosis, as it is an viral infection and clindamycin is not anti-viral. Simple means like adequate fluids, proper rest, healthy diet may help in its early recovery. OTC analgesics may help in fever, pain & sore throat. Still, some times streptococcal infection of throat & mononucleosis may be present simultaneously, hence in such cases, clindamycin may have its role. Definitely, clindamycin may also result in allergic symptoms in prone cases. Particularly, if one is suffering from membranous enterocolitis, ulcerative colitis or Crohn s disease, use of clindamycin is strictly contra-indicated. Take care. Hope I have answered your question. Let me know if I can assist you further. Regards, Dr. Satnarain Bansal, General & Family Physician