Hello, Welcome to HCM, There are many causes for skin blisters, but all the skin blisters should managed properly, otherwise it will lead to secondary bacterial infection. All the blisters should be managed by If the blister has burst, don’t peel off skin Apply antiseptic and a dressing Don’t use tape alone for the dressing Change the dressing daily and re-apply antiseptic. Avoid ‘folk remedies’ like applying turmeric,coffee,chilli and butter. Antibiotics, in the case of a bacterial infection Antifungal preparations, in the case of fungal infection Antiviral preparations, in the case of viral infection Treatment for any underlying allergy. These are the basic steps in management of blisters with pus formation. Thank you.