hi i had gone through your query and understand your concerns. i would come up with,the most possibilities to fit your condition .these include 1.first possibility is,DEGENERATIVE CHANGES in the cervical spine may lead to CERVICAL SPONDYLOSIS and cause the cervicao brachial neuralgia, the changes in the knee joint may cause OSTEOARTHRITIS of the knee joint 2.second possibility is,ALLERGY-SINUSITIS; the possible causes include; -allergy -inadequate nutrition -pollution of air and water -general poor health -underlying dental infections -excessive consumption of starchy and sugary foods and milk -stress -DYSBIOSIS;is a condition where there is the presence of abnormal intestinal bacteria.this is the often major underlying cause of food sensitivity. treatment option; i advise you taking Homeopathic medicines gives safe and permanent cure for your complaints consult your local homeopathic physician for correct diagnosis of the case and remedy to fit your complaints I hope this is helpful for you, thank you