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Dr. Andrew Rynne
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Dr. Andrew Rynne

Family Physician

Exp 50 years

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Suffering From Eczema, Used Clobetasol Cream, Skin Discolored. Permanent Discoloration?

Hi,

I suffer from eczema, and it came back after sometime(upper arms, sides of the abdomen), last night I used Clobetasol cream 0.05% I had leftover from my previous eczema episode (since I do not have health insurance anymore).
This morning my skin was a tad discolored (may be 2 skin tones lighter) exactly on the areas I put the cream. I got scared and did not put more Clobetasol tonight.

Is this discoloration permanent?
Thanks for your help.
Wed, 17 Apr 2013
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Dermatologist 's  Response
Hi, Thanks for posting your query to HCM.
Topical Steroids have the tendency to cause side effects when used for long period of time. Especially the high potency steroid (clobetasol) are known for the side effects such as atrophy of skin. As per your problem you have applied clobetasol for only one night, so it is quite unlikely for the side effect of atrohic changes to appear in a single day. The only reason might be you applied the cream in lot of quantity so because of the remnants of the cream it is appearing as discolored i.e. hypo-pigmented. Though epidermal atrophy is possible but is not that early to appear in a night, and if occurs is reversible. So, kindly relax yourself as this discoloration is totally reversible even if think of epidermal atrophy in that short period of time!!
But be careful to apply your steroid cream done under dermatological guidance. The simple fundamental is - a pea size amount of cream on the tip of finger is sufficient for area of palm size known as 1FTU.
So do take care next time,
with best health wishes
Dr Sanjay K Kanodia
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Suffering From Eczema, Used Clobetasol Cream, Skin Discolored. Permanent Discoloration?

Hi, Thanks for posting your query to HCM. Topical Steroids have the tendency to cause side effects when used for long period of time. Especially the high potency steroid (clobetasol) are known for the side effects such as atrophy of skin. As per your problem you have applied clobetasol for only one night, so it is quite unlikely for the side effect of atrohic changes to appear in a single day. The only reason might be you applied the cream in lot of quantity so because of the remnants of the cream it is appearing as discolored i.e. hypo-pigmented. Though epidermal atrophy is possible but is not that early to appear in a night, and if occurs is reversible. So, kindly relax yourself as this discoloration is totally reversible even if think of epidermal atrophy in that short period of time!! But be careful to apply your steroid cream done under dermatological guidance. The simple fundamental is - a pea size amount of cream on the tip of finger is sufficient for area of palm size known as 1FTU. So do take care next time, with best health wishes Dr Sanjay K Kanodia