I am no expert in dermatology so I can not comment on the effects of cannabis on Accutane
but I can definitely tell you from studies it has been proved beyond doubt that smoking cannabis affects your mental health weather you are on any medication or not.
Also there may be other enzymatic side effects of smoking
itself which may alter the amount of prozac
that your daily dose is made available in the blood.
Best thing to do is, STOP SMOKING CANNABIS.