The main risk following splenectomy is overwhelming infection, or post splenectomy sepsis. The risk of post-splenectomy sepsis can be reduced by vaccinations and preventative antibiotics. If you were not vaccinated prior to surgery, you should arrange to get the vaccines once you have completely recovered from the operation. Haemophilius Influenzae type B (Hib), Pneumococcal vaccine, Meningococcal group A, C, Y, W135 and B should be taken. The vaccination schedule will be advised by your General Physician. You will also need either daily antibiotics or emergency antibiotics when you are unwell. That will be again prescribed by your Physician. Seek medical attention when unwell, present to your GP or nearest Emergency Department. Look for high fever, cough with phlegm, flu-like illness and sore throat. Take special care to avoid infections.