Hi ! Good morning. I am Dr Shareef answering your query. For the gastro esophageal reflux, I would suggest you the following: 1) Elevate the head end of the bed with two blocks on each side, so that the regurgitation does not occur while lying down, and the contents of esophagus and stomach flow down with gravity. 2) Some modification in your diet like more of roughage, enough liquids, avoidance of oily, fried, and fast food, and avoidance of alcoholic beverages and smoking if you do. 3) Regular routine exercises like morning walk depending on your medical fitness. 4) Prescription for a prokinetic agent and a proton pump inhibitor for symptomatic relief and to have a control on the acid production and facilitate movement of gastric contents downwards. 5) Routine stool test for ova and cyst and treat them if positive. Enlargement of the spleen might be a separate entity by itself, unless the GERD was part of a systemic problem like some auto immune disorders. You might have to get yourself assessed and investigated in detail by your treating doctor to know the cause of the enlarged spleen. I hope this information would help you in discussing with your family physician/treating doctor in further management of your problem. Please do not hesitate to ask in case of any further doubts. Thanks for choosing health care magic to clear doubts on your health problems. I wish you an early recovery. Dr Shareef.