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How long methadone can stay in urine?

24 10 mgm methadone taken in 5 day period- how lonh will they stay in your urine?
Asked On : Wed, 19 Jan 2011
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General & Family Physician 's  Response
Methadone has a slow metabolism and very high fat solubility, making it longer lasting than morphine-based drugs. Methadone has a typical elimination half-life of 15 to 60 hours with a mean of around 22. The drug is eliminated in even after this time. However, metabolism rates vary greatly between individuals, ranging from as few as 4 hours to as many as 130 hours,or even 190 hours.This variability is apparently due to genetic variability between individuals.
Answered: Thu, 20 Jan 2011
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