Hi, I guess your concern about for painful menses plus conceiving for the next baby. Treatment information given by you seems correct. Endometriosis is a health problem in which pt will have painful menses and difficultly in conceiving. The surgery and medicines (Zoladex, Prolifen as told by you) is usually given for endometriosis treatment. But, when the surgery was done and when the medicines were started, this information is not shared by you. The dosing of medicines is also not told by u.so i cant comment on the medicines. Dont worry, once the problem of endometriosis is solved you can conceive for next baby. My suggestions: 1. Usually it takes some time for the medicines to have their effect. Sometimes the medicines start working early and sometimes it takes little extra time. 2. So have patience. Wait for few more days. if still their is no improvement in painful menses, revisiting your treating doctor. Your other concern is to conceive for next baby. Endometriosis is one of the cause of infertility (infertility in medical term means unable to conceive). So a patient on treatment for endometriosis is usually having difficulty in conceiving till successful treatment of the problem. My advice: 1. Revisit your treating doctor, to discuss about conceiving for the next baby and presence of painful menses inspite of taking medicines. 2. You may also consult a nearby infertility specialist. I hope the information is useful, informative and helpful. I wish and pray almighty that your son will be getting a cute sibling as soon as possible. Hope I have answered your query. Let me know if I can assist you further. Regards, Dr. Sudha Rani Panagar