Your query that out of 4 children product of consanguinous parentage, 3 children have growth abnormality and in addition elder one has Arnold chiari malformation1 that is tonsillar herniation .
Arnold chiari malformation is a development abnormality , there is no relation to growth abnormalities .However if child has asssociated hydrocephalus
and compression of hypothalomo pituitary tract growth of the child can be affectedConsult neurologist
for detail examination whether it is really growth of child is affected or you meant to say spasticity
of lower limbs
and global development delay.
Dr Sandhya Manorenj
Hi tech city Hyderabad