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What Does This Triple Marker Screen Test Report Indicate?
Question: Hi,
We recently had triple marker test for my wife. I would like to attach the reports so a specialist doctor can evaluate it.
Can you please tell me what is health risk once you go through the reports.
Regards,
Veetesh
We recently had triple marker test for my wife. I would like to attach the reports so a specialist doctor can evaluate it.
Can you please tell me what is health risk once you go through the reports.
Regards,
Veetesh
Brief Answer:
Amniocentesis advised
Detailed Answer:
Hello mam, thanks for trusting health care magic.
I have seen the attached reports and sad to inform you that the report is not good.
To explain it in Simple language -
Normal risk of trisomy 21 is 1 in 250 females of your age that means that if 250 women get this test done then only one patient with these levels of enzymes will be carrying a baby with trisomy 21.
In your case the level of enzymes are increased to the levels that one female out of 202 will be carrying an abnormal child.
So it becomes an indication for further evaluation in the form of amniocentesis which is though a Simple procedure bit carries a risk abortion in 4% of cases.
In amniocentesis small fluid is withdrawn from the water around the baby inside uterus and then fetal cells are evaluated for trisomy via karyotyping.
All the best.
Regards
Dr Manisha
Amniocentesis advised
Detailed Answer:
Hello mam, thanks for trusting health care magic.
I have seen the attached reports and sad to inform you that the report is not good.
To explain it in Simple language -
Normal risk of trisomy 21 is 1 in 250 females of your age that means that if 250 women get this test done then only one patient with these levels of enzymes will be carrying a baby with trisomy 21.
In your case the level of enzymes are increased to the levels that one female out of 202 will be carrying an abnormal child.
So it becomes an indication for further evaluation in the form of amniocentesis which is though a Simple procedure bit carries a risk abortion in 4% of cases.
In amniocentesis small fluid is withdrawn from the water around the baby inside uterus and then fetal cells are evaluated for trisomy via karyotyping.
All the best.
Regards
Dr Manisha
Above answer was peer-reviewed by :
Dr. Chakravarthy Mazumdar
Thank you for the answer.
So can you please suggest the exact procedure to follow now and which medical department handles this type of tests.
Also how much it costs?
So can you please suggest the exact procedure to follow now and which medical department handles this type of tests.
Also how much it costs?
Brief Answer:
Fetal medicine
Detailed Answer:
Fetal medicine specialist usually handles this and the cost may vary from 20,000-50,000 depending on the hospital but is available at minimal costs at PGI and XXXXXXX hospital.
Just get yourself registered and do it as early as possible because it will take 3-7 days for the report to come.
And abortion if at all needed for abnormal fetus is only possible till 20 weeks og pregnancy so plan accordingly so that everything is done till 19 weeks of pregnancy.
In case you need any other advice please feel free to ask anytime.
All the best.
Fetal medicine
Detailed Answer:
Fetal medicine specialist usually handles this and the cost may vary from 20,000-50,000 depending on the hospital but is available at minimal costs at PGI and XXXXXXX hospital.
Just get yourself registered and do it as early as possible because it will take 3-7 days for the report to come.
And abortion if at all needed for abnormal fetus is only possible till 20 weeks og pregnancy so plan accordingly so that everything is done till 19 weeks of pregnancy.
In case you need any other advice please feel free to ask anytime.
All the best.
Above answer was peer-reviewed by :
Dr. Chakravarthy Mazumdar
Thank you XXXXXXX
Is it really mandatory to get this procedure done?? Because I assume nearly 80% of the women who are pregnant might not go for triple marker test at all, at least I am aware of.
Also my family and my wife's family doesn't have any pre genetic disorder births. I understand that the risk ratio is 1:202, is it really true that we will get affected?
Is it really mandatory to get this procedure done?? Because I assume nearly 80% of the women who are pregnant might not go for triple marker test at all, at least I am aware of.
Also my family and my wife's family doesn't have any pre genetic disorder births. I understand that the risk ratio is 1:202, is it really true that we will get affected?
Brief Answer:
You should get it done
Detailed Answer:
See the risk is 1 in 202 women but you cannot say she is amongst 201 or the one!
Moreover the very purpose of getting triple test will be defeated and obviously money wasted plus tension of risk till delivery.
Now the decision is yours as definitely i understand that you are scared of the risk of abortion but then again the risk of congenitally malformed baby has no match.
In my opinion i advice all my patients to opt for it.
You should get it done
Detailed Answer:
See the risk is 1 in 202 women but you cannot say she is amongst 201 or the one!
Moreover the very purpose of getting triple test will be defeated and obviously money wasted plus tension of risk till delivery.
Now the decision is yours as definitely i understand that you are scared of the risk of abortion but then again the risk of congenitally malformed baby has no match.
In my opinion i advice all my patients to opt for it.
Above answer was peer-reviewed by :
Dr. Chakravarthy Mazumdar
Thank you.
I inquired in my city about the procedure. Is it true that Amniocentesis consists of two levels of tests, one is FISH test and second one is something else(?) which takes two weeks for report output.
Can you please tell me a bit about these two tests as I have no idea?
Can you please also suggest me what exact tests I need to opt as part of Amniocentesis, as I may go for Amniocentesis later next week.
Just today we had another round of triple test in 17th week. May be by this Saturday I will be in a position to decide everything.
I inquired in my city about the procedure. Is it true that Amniocentesis consists of two levels of tests, one is FISH test and second one is something else(?) which takes two weeks for report output.
Can you please tell me a bit about these two tests as I have no idea?
Can you please also suggest me what exact tests I need to opt as part of Amniocentesis, as I may go for Amniocentesis later next week.
Just today we had another round of triple test in 17th week. May be by this Saturday I will be in a position to decide everything.
Brief Answer:
Karyotyping alone
Detailed Answer:
Yes dear.
Since you have time as yet you can get Simple karyotyping done because your wife young so need to get FISH Test done which is costlier and is usually advised if heriditory or metabolic disorders are suspected.
So in your case karyotyping alone will suffice.
Wish you all the best and i hope everything comes out normal and thus tension free antenatal period.
Karyotyping alone
Detailed Answer:
Yes dear.
Since you have time as yet you can get Simple karyotyping done because your wife young so need to get FISH Test done which is costlier and is usually advised if heriditory or metabolic disorders are suspected.
So in your case karyotyping alone will suffice.
Wish you all the best and i hope everything comes out normal and thus tension free antenatal period.
Above answer was peer-reviewed by :
Dr. Chakravarthy Mazumdar
Thank you.
I heard both FISH and Karyotyping results look for the same disorders, but FISH result comes very quickly. Is it true and is that the only difference?
So this Karyotyping test will get all the complete details about the Downs Syndrome etc?
I heard both FISH and Karyotyping results look for the same disorders, but FISH result comes very quickly. Is it true and is that the only difference?
So this Karyotyping test will get all the complete details about the Downs Syndrome etc?
Brief Answer:
yes results come early
Detailed Answer:
No dear there are two differences -
1) FISH results come early (definitely)
2) FISH can also locate gene disorders so is for specific disorders too.
yes results come early
Detailed Answer:
No dear there are two differences -
1) FISH results come early (definitely)
2) FISH can also locate gene disorders so is for specific disorders too.
Above answer was peer-reviewed by :
Dr. Chakravarthy Mazumdar
Hi XXXXXXX
As I said earlier I had a another round of TMS earlier this week to double check the first report results. I got the report yesterday and I am attaching the same for your reference.
Could you please go through the latest report and let me know further course of action?
As I said earlier I had a another round of TMS earlier this week to double check the first report results. I got the report yesterday and I am attaching the same for your reference.
Could you please go through the latest report and let me know further course of action?
Brief Answer:
3D ultrasound advised
Detailed Answer:
Hi I have seen the report and though the levels are in normal limits but still age related risk is high.
In case you still are not interested in amniocentesis then at least get a 3D ultrasound at 24-26 weeks.
And also keep a regular follow up with your doctor.
Take care
3D ultrasound advised
Detailed Answer:
Hi I have seen the report and though the levels are in normal limits but still age related risk is high.
In case you still are not interested in amniocentesis then at least get a 3D ultrasound at 24-26 weeks.
And also keep a regular follow up with your doctor.
Take care
Above answer was peer-reviewed by :
Dr. Chakravarthy Mazumdar
Thank you.
Can you tell me the cut off range for age risk? Report is showing 1:1300+. So is it something to worry about?
Our doctor suggested to have tiffa scan after 22 weeks. Is it the same scan you are also advising?
Though the report shows normal risk values we may have to consider amniocentesis?
Can you tell me the cut off range for age risk? Report is showing 1:1300+. So is it something to worry about?
Our doctor suggested to have tiffa scan after 22 weeks. Is it the same scan you are also advising?
Though the report shows normal risk values we may have to consider amniocentesis?
Brief Answer:
3D scan will suffice
Detailed Answer:
Actually she is low risk according to the second report but still slightly increased risk as compared to other women who are of your age.
So 100% sure option is amniocentesis bit as is invasive so 3D scan can serve the purpose to much extent which is the same as your doctor suggested.
But keep a regular follow up in the form of antenatal check ups and growth scan till term.
Wish you a healthy child soon.
3D scan will suffice
Detailed Answer:
Actually she is low risk according to the second report but still slightly increased risk as compared to other women who are of your age.
So 100% sure option is amniocentesis bit as is invasive so 3D scan can serve the purpose to much extent which is the same as your doctor suggested.
But keep a regular follow up in the form of antenatal check ups and growth scan till term.
Wish you a healthy child soon.
Note: Revert back with your gynae reports to get a clear medical analysis by our expert Gynecologic Oncologist. Click here.
Above answer was peer-reviewed by :
Dr. Chakravarthy Mazumdar
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