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Rise In PSA After Prostatectomy, Taken Casodex

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Posted on Fri, 25 May 2012
Question: Rise in PSA after prostatectomy
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I had surgery in March 2010, subsequently, my first PSA test in May 2010 was 0.1, the second in November 2010 was 0.2, and now the third in February 2011 is 0.3. My doctor recommended that I take Casodex 50mg. for three months and then take another PSA test, however, I am worried about the increase. Should I be? What other options do I have?
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Answered by Dr. Rajiv goel (10 hours later)
Dear,

You are certainly witnessing an increase in PSA and the possibilities are that you have a residual prostatic tissue, recurrence of the disease locally or metastases. Your PSA has been rising very slowly and I shall not recommend any active intervention at present.

However, I shall not advise you to start on Casodex as it shall surely normalize the PSA and we may miss the progression of disease. I shall suggest you to repeat PSA after 3 months and if it is still raising then you shall have to be investigated further with local examination, TRUS (Trans Rectal Ultrasonography of Prostate), liver function test, chest X-ray, bone scan.
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Above answer was peer-reviewed by : Dr. Shanthi.E
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Dr. Rajiv goel

Urologist

Practicing since :1998

Answered : 581 Questions

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Rise In PSA After Prostatectomy, Taken Casodex

Dear,

You are certainly witnessing an increase in PSA and the possibilities are that you have a residual prostatic tissue, recurrence of the disease locally or metastases. Your PSA has been rising very slowly and I shall not recommend any active intervention at present.

However, I shall not advise you to start on Casodex as it shall surely normalize the PSA and we may miss the progression of disease. I shall suggest you to repeat PSA after 3 months and if it is still raising then you shall have to be investigated further with local examination, TRUS (Trans Rectal Ultrasonography of Prostate), liver function test, chest X-ray, bone scan.