Hi,Dear,Thanks for your query to HCM virtual Clinic. I studied your query in all the details put forth by you. I understood your health concerns. Cause of the health problems you queried- There are many causes of the sore lump on the top of the leg,after leg amputation like,Amputation neuroma,Amputation dermatoses(skin infections/infestations,Amputation wound Granuloma,Cracked stump skin,phantom limb pain/ soreness/ or a compromised skin circulation with skin wound and infection. As the soreness is while putting your artificial leg and is caused around the lump developed, -Cause in your case seems to be either from Amputation stump skin tag with sore skin eczema,or skin infection with soreness/ Or could be due to the Amputation neuroma-due to excessive lumpy mass of the amputated nerve end in the amputated leg stump. As I don t have any first hand information or a photograph of the part, I suggest you to consult ER Ortho-surgeon,who would rule out other causes and would treat it according to the cause of this stump lump on the top of the amputated leg. Remedy- So till the time you consult ER Ortho Surgeon and get his definitive opinion after above investigations,DON T WORRY AT ALL but you need to be worried as it would complicate into some other serious problem with your amputed leg. And act fast on the above suggestions,which helps you to plan treatment with your ER OrthoSurgeon. Hope this would resolve your query with full satisfaction. Welcome for any further query in this regard to ME by direct question at HCM. Write excellent review and hit thanks, to narrate your experience ,which would improve my rating for many other visitor s to HCM. Wishing you fast recovery. Have a good day. Dr.Savaskar M.N. Senior Surgical Consultant. M.S.Genl-CVTS