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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Pain Relief Medicine Can Be Taken With Losartan?

I have been prescribed Losartan in addition to Nefedipine for my hypertension. I have looked up several OTC pain relievers (Aspirin, Aleve, Advil, Excedrin, & Ibuprofen) that all have adverse interactions with Losartan. Is Tylenol the only OTC pain reliever I can take that won t have an adverse interaction with Losartan? Thank you.
Mon, 14 Nov 2016
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General & Family Physician 's  Response
Hi & Welcome.

Paracetamol or Acetaminophen can be taken along with Losartan.

OTC pain relievers (non-steroidal anti-inflammatory drugs) like Aspirin or Ibuprofen can reduce the blood pressure lowering effects of Losartan.

Long-term use of these medications can cause retention of salt and water in various tissues and this can alter the efficacy of Losartan.

In addition, these medications may affect your kidney function, especially when they are used together frequently or chronically.

Paracetamol or Tylenol (Acetaminophen) is often the best choice for people with high BP while taking treatment with Losartan. However, high doses of Tylenol can damage the liver, so take the lowest dose you can to get enough pain relief. Never take more than 4,000 milligrams (mg) a day. That’s equal to twelve 325 mg pills.

If Tylenol does not work, ask your treating doctor about using a stronger analgesic (painkiller) like Tramadol for a short time.

Hope to have answered your query.
Wishing you best of your health.
A feedback is appreciated.



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What Pain Relief Medicine Can Be Taken With Losartan?

Hi & Welcome. Paracetamol or Acetaminophen can be taken along with Losartan. OTC pain relievers (non-steroidal anti-inflammatory drugs) like Aspirin or Ibuprofen can reduce the blood pressure lowering effects of Losartan. Long-term use of these medications can cause retention of salt and water in various tissues and this can alter the efficacy of Losartan. In addition, these medications may affect your kidney function, especially when they are used together frequently or chronically. Paracetamol or Tylenol (Acetaminophen) is often the best choice for people with high BP while taking treatment with Losartan. However, high doses of Tylenol can damage the liver, so take the lowest dose you can to get enough pain relief. Never take more than 4,000 milligrams (mg) a day. That’s equal to twelve 325 mg pills. If Tylenol does not work, ask your treating doctor about using a stronger analgesic (painkiller) like Tramadol for a short time. Hope to have answered your query. Wishing you best of your health. A feedback is appreciated.