Hello, I have unilateral leg edema (left leg). A little hx: I am a 61 year old female and experienced edema of my left leg in March after a 3.5 hour flight from MD to TX. I saw my PCP a week after returning home as my leg was still swollen. I was sent for lab work and an ultrasound. My D-Dimer blood test was elevated however, the ultrasound of my left leg was normal. Nothing more was done and eventually the edema subsided. Over the past few weeks I’ve noticed some slight edema in my left foot and ankle that seemed to come and go. Wednesday I was a passenger in a car for about 5 hours with only one break to walk around. Afterwards, I was at an event where I was sitting for an extended period of time. My left leg was quite swollen when I got home. Since then, I have tried to keep it elevated whenever I sit down and I elevate it in bed at night when I go to sleep. Even though the swelling is not as pronounced as it was Wednesday evening, I am a little concerned that I may have a serious vascular issue. In addition, I should probably mention that 30 years ago I had recurrent thrombophlebitis and was diagnosed with vasculitis a year or two afterwards. I have not had a blood clot since then nor a flare up of vasculitis. Your thoughts and suggestions are most appreciated.