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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What is the protocol in switching a patient off decanoate IM to fluphenazine hydrochloride PO ?

In the setting of the current Prolixin decanoate shortage what is the protocol in switching a patient off decanoate IM to fluphenazine hydrochloride PO. I know the equivalency of approximately 12.5mg dec = 10mg hcl but unsure when to intiate the oral medication and at what dose. Any information appreciated - thank you.
Wed, 26 Jun 2013
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Psychiatrist 's  Response
Hi,
Thanks for using healthcare magic.

I have gone through your available history.

Trifluoperaizine usually achieve steady state plasma level within 1-2 week duration. But it may vary from individual to individual.

So you can start trifluoperazine 10 mg along with last dose of injectable trifluoperazine.

You should consult your psychiatrist before changing any dose schedule.

I hope I have addressed your concern.

Thanks.
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What is the protocol in switching a patient off decanoate IM to fluphenazine hydrochloride PO ?

Hi, Thanks for using healthcare magic. I have gone through your available history. Trifluoperaizine usually achieve steady state plasma level within 1-2 week duration. But it may vary from individual to individual. So you can start trifluoperazine 10 mg along with last dose of injectable trifluoperazine. You should consult your psychiatrist before changing any dose schedule. I hope I have addressed your concern. Thanks.