Sign-in to Ask A Doctor - 24x7
OR
Sign in with GoogleGet your health question answered instantly from our pool of 18000+ doctors from over 80 specialties
What Is The Mode Of Action Of Diclofenac?
Hi can you please explain to me, what happens to diclofenac when it goes from the small intestine. How does it go from small intestine to the liver sinusoid, which artery does it come in from. Also how does it get from the liver to the target site of inflamation?
Tue, 9 Dec 2014
Hello
Welcome here.
The drug get absorbed via the intestinal epithelium reaches its blood vessels, enters the portal circulation, enter liver sinusoids and is converted to active metabolite. The active metabolite is reached to site of inflammation.
Hope this answers you.
Thanks.
Welcome here.
The drug get absorbed via the intestinal epithelium reaches its blood vessels, enters the portal circulation, enter liver sinusoids and is converted to active metabolite. The active metabolite is reached to site of inflammation.
Hope this answers you.
Thanks.
I find this answer helpful
Note: For more detailed guidance, please consult an Internal Medicine Specialist, with your latest reports. Click here..
Disclaimer: These answers are for your information only and not intended to replace your relationship with your treating physician.
This is a short, free answer.
For a more detailed, immediate answer, try our premium service
[Sample answer]
Related questions you may be interested in
Loading Online Doctors....