associated uveitis usually affects the front of the eye causing so call iritis... this is typically treated with steroid eye drops. A common complication of severe iritis
is posterior synechia which occurs when the inflamed irits adheres to the crystalline lens. This results in the irregular pupil that you are describing. No treatment is indicated or advisable since cutting these synechiae risks damaging the lens which would result in cataract
formation. These synechia are however eventually lysed at the time of cataract removal so the pupil regains a more normal shape.
When you see small sized particles like floaters, these are always near the retina. Up to 50% of HLA B27 assoc uveitis patients will at some point develop posterior uveitis
. Unlike anterior uveitis
, posterior uveitis may causes less pain and its principle symptom is floaters.
On examination, patients with posterior uveitis will have cells in the vitreous. These patients require more aggressive treatment --- often with periocular or oral steroids
. These floaters usually improve once the inflammation improves.
from HLA B27, though easy to treat, often recurs many times over the years. For this reason, ALL of my patients have steroid drops available at home to start treatment at the first sign of trouble to minimize complications. Good Luck.