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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Causes Varied Results For VDRL Test?

hi i m 36 year old women. there is a problem when i make my vdrl tesl from the lab. one company strip of this test give me vdrl positive but the other strip of test give result negative of vdrl. please give me solution of this problem because after two month my marriage in abroad
Thu, 17 Mar 2016
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General & Family Physician,  's  Response
Hello dear,
VDRL is test for syphilis , it detect antibodies against trepenoma pallidium
There are various cause in which VDRL test give false positive reaction:
1. Viral infection
2. Malaria
3. Pnemonia
4. Tuberculosis
5. IV drug users
6. HIV

So if you suspect above any cause you should repeat test after taking treatment of that.

VDRL test will come positive after 3-5 week of trepenoma infection. so if you did test before 3 week it may be false negative.
If you have symptoms like ulcer anywhere in body that is painless and non itching (Mostly on mouth, vagina, palm and hand) and nodule around that it suggest syphilis.

Then you should consult with doctor.
And you should go for fluorescent treponomal antibody absorbance test that is very sensitive.

Hope this may help you.
wish you good health

Best regards
Dr. Sagar

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What Causes Varied Results For VDRL Test?

Hello dear, VDRL is test for syphilis , it detect antibodies against trepenoma pallidium There are various cause in which VDRL test give false positive reaction: 1. Viral infection 2. Malaria 3. Pnemonia 4. Tuberculosis 5. IV drug users 6. HIV So if you suspect above any cause you should repeat test after taking treatment of that. VDRL test will come positive after 3-5 week of trepenoma infection. so if you did test before 3 week it may be false negative. If you have symptoms like ulcer anywhere in body that is painless and non itching (Mostly on mouth, vagina, palm and hand) and nodule around that it suggest syphilis. Then you should consult with doctor. And you should go for fluorescent treponomal antibody absorbance test that is very sensitive. Hope this may help you. wish you good health Best regards Dr. Sagar