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Dr. Andrew Rynne
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What causes low levels of ALP with elevation in AST and ALT levels?

Two years ago my doctor pointed out my ALP was low at 33 (but AST normal at 15 and ALT normal at 14. Now exactly two years later my ALP came back even lower at 30, and my AST had jumped up to 74 and ALT to 35. I have had mid & lower back pain for about two years, should I worry? I rarely drink alcohol (more in the past), but I love spicy food and I work out quite often. My mother had gall stones. Any advice?
Thu, 21 Jul 2016
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  Anonymous's Response
's  Response
Usually high levels of ALP is associated with Liver/gallbladder diseases. And you shouldn't be worried about raised AST because ALT is more specific when it comes to Alcoholic Liver Disease. AST can also be produced from muscle tiisues and myocardium so your working out would probably explain that.
Anyway your problem is low ALP levels. This usually indicates malnutrition or celiac disease. Celiac disease/Gluten enteropathy is an autoimmune disease and needs treatment. Now if you're a healthy adult I suggest that some multivitamin syrups going to help you. However I recommend you to visit your physician and get the screening tests for gluten enteropathy done.
Hope this helps :)

Dr Philip
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