Hi, Leg cramps that occur during sleep are often referred to as nocturnal leg cramps. These cramps are involuntary muscle contractions that can cause discomfort or pain and can wake a person up from their sleep. They commonly affect the calf muscles, but can also occur in the thighs or feet. There are many possible causes of leg cramps, including dehydration, electrolyte imbalances, overexertion of muscles, and medical conditions such as peripheral artery disease, diabetes, and kidney or liver disease. In some cases, there may be no obvious cause. Here are some tips for treating and preventing leg cramps: * Stretch before bed: Gently stretch the muscles in the legs before going to bed. * Stay hydrated: Drink plenty of fluids throughout the day to prevent dehydration, which can contribute to leg cramps. * Electrolyte balance: Make sure you are getting enough electrolytes such as potassium, magnesium, and calcium in your diet, which can also help prevent leg cramps. * Take a warm bath: Taking a warm bath before bed can help relax the muscles and relieve tension. * Massage: Massaging the affected muscles may also help alleviate the cramps. * Medications: There are some over-the-counter pain relievers and muscle relaxants that can be used to help alleviate leg cramps, but it s always best to consult a doctor before starting any new medication. If these remedies do not help, it is recommended to see a doctor for further evaluation and treatment. Your wife s doctor can help determine the underlying cause of the leg cramps and recommend the appropriate treatment. If there is an underlying condition, treating it may help alleviate the leg cramps. Take care. Hope I have answered your question. Let me know if I can assist you further. Regards, Dr. Priyanka, General & Family Physician