Hello. When a cause can be found, the itching is usually due to irritation of the skin around the anus. Some of the most common irritants include the following: 1. Perfumes, chemicals, or dye on toilet paper can cause an allergic reaction. 2. Moisture from sweat or diarrhea may cause itching. If the anal skin stays wet, the skin begins to break down. 3. Some foods irritate the anus when they are expelled during a bowel movement 4. Infections such as pinworms, yeast, and genital warts can cause itching. 5. Hemorrhoids, which cause painful swelling of blood vessels in the anal area, can cause itching Try not to irritate the skin even more by scrubbing the area with soap. This will only cause more irritation and itching. Gentle cleaning with water helps the area heal. Other home therapies include the following: 1. Change to a plain, soft, unscented toilet paper. 2. If toilet paper feels too abrasive, try cleaning with unscented baby wipes or cotton moistened with mineral oil. Dry with cotton afterward to remove any moisture. Many times, baby wipes can exacerbate anal itching if used long-term. 3. Wear loose-fitting cotton underwear that allows sweat to evaporate Over-the-counter medicines such as creams containing hydrocortisone or zinc oxide can provide some relief; however, apply sparingly and notify your health care practitioner prior to using them. 4. Avoid food irritants and eat a high-fiber diet Most causes of anal itching can be readily treated. 1. Hydrocortisone cream (1%) applied locally for no more than two weeks (to avoid skin damage). 2. Pinworms and bacterial infections are treated with prescription anti-parasitic pills. 3. Yeast infections and many rashes improve with creams. 4. Skin lesions such as warts or hemorrhoids are removed with minor surgical procedures with regards- Dr Sanjay kini