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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Causes High Prolactin Levels In Case Of Pituitary Microadenoma?

Hi there.
I was diagnosed with hypothyroidism and a 4mm pituitary microadenoma 1 year ago. I have been on Synthroid 100 and for the last year, I have taken .25 cabergoline 2x weekly.
I just had a followup MRI and to my shock, the tumor is now a "larger T2 hyperintense, T1 isointense 7x9x7 mm oval focus of decreased enhancement, with increased enhancement over dynamic imaging becoming relatively hyperintense compared to the adjacent pituitary gland consistant with a pituitary adenoma."
Throughout this year, my prolactin was high, even though most of the labs stated that they were in the normal range. My doctor informed me that because I have an adenoma, these ranges are not applicable to me. What??? Now he tells me!
So, now they want to double my dose of cabergoline to .5 2x weekly and then after 4 weeks test my Growth Hormones, to make sure I don't have a "chimera".
Shouldn't they have tested that earlier? Any information or guidance would be greatly appreciated! -Annette
Fri, 20 Jan 2017
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Endocrinologist 's  Response
Hi,

I have gone carefully through your concern. In most of the cases prolactin secreting microadenoma of the pituitary gland, responds good to cabergoline and it's size shrinks after dome years of treatment. When a prolactinoma is diagnosed, other hormones produced by the pituitary gland are not routinely checked. In cases like this, when the size of the adenoma increases instead of decreasing, other hormones are checked to exclude another production by the tumor.

So, do not worry because this is a normal way of monitoring a pituitary tumor. Wish you good health.

Best wishes,
Dr. Mirjeta
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What Causes High Prolactin Levels In Case Of Pituitary Microadenoma?

Hi, I have gone carefully through your concern. In most of the cases prolactin secreting microadenoma of the pituitary gland, responds good to cabergoline and it s size shrinks after dome years of treatment. When a prolactinoma is diagnosed, other hormones produced by the pituitary gland are not routinely checked. In cases like this, when the size of the adenoma increases instead of decreasing, other hormones are checked to exclude another production by the tumor. So, do not worry because this is a normal way of monitoring a pituitary tumor. Wish you good health. Best wishes, Dr. Mirjeta