Hi Thanks for posting yoru query on HCM I have read and understood your concern Fever in an infant may be caused by viral, bacteria or parasitic infection.Persistence of fever on anti-pyretics and antibiotics may suggest two things: -Germ in cause not responding to the antibiotic -Or fever may be caused by a parasite like malaria parasite if in a risk zone I will suggest you try the following: *Physical measures to control fever like light dresses and application of wet compresses *Continue with anti-pyretic and antibiotics as prescribed by your Doctor If symptoms persist, you see the Doctor for reevaluation and tests like malaria test and a blood culture if need be.Your Doctor may also consider IV anti-pyretics and antibiotics if symptoms persist Hope this will help.You may write back if more concerns Best regards Dr Mbuomboh