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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Causes High ALT And AST?

I have a history of high ALT and AST (currently and recently tested they are: ALT 129 and AST 73). Doctors have done many tests and even a liver biopsy. I do not have Hep A, B or C; my liver biopsy didn t even show fatty liver. My gall bladder was removed about 10 years ago, but well before that even I tested high ALT and AST. One doctor tested for autoimmune hep and my markers came by positive but low. I was just placed on generic Lipitor and Losartan for blood pressure. Any thoughts?
Mon, 29 Dec 2014
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Radiologist,  's  Response
Hello

Increased ALT may indicate liver injury.It may be due to many reasons like hepatitis,alcohol intake,altered lipid profile, medicines,auto immune causes etc.
It may be related to autoimmune heaptitis in your case.

You have been prescribed right medicines.Lipitor is advised for altered lipid profile.
I also suggest tablet ursodeoxycholic acid 300 mg twice daily for three months to my patients.It helps in regeneration of liver cells.

AST in non specific and it increases in many conditions.

Get well soon.
Take Care
Dr.Indu Bhushan
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What Causes High ALT And AST?

Hello Increased ALT may indicate liver injury.It may be due to many reasons like hepatitis,alcohol intake,altered lipid profile, medicines,auto immune causes etc. It may be related to autoimmune heaptitis in your case. You have been prescribed right medicines.Lipitor is advised for altered lipid profile. I also suggest tablet ursodeoxycholic acid 300 mg twice daily for three months to my patients.It helps in regeneration of liver cells. AST in non specific and it increases in many conditions. Get well soon. Take Care Dr.Indu Bhushan