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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Causes Headaches While On Phenylephrine And Guaifenesin?

I went to the VA hospital yesterday and was diagnosed with a upper respiratory infection and was then given Phenylephrine Hcl 10mg tab along with guaifenesin 400mg tab. I would like to ask is the first drug causing me to have headaches and if I cut the second one in half will that cause any harm?
Tue, 22 Mar 2016
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General & Family Physician,  's  Response
Hello dear
Understand your concern.
Phenylephrine is a act by stimulating alfa adreneric receptor.
It cause vacoconstriction of nose blood vesseles and reduce inflammation & congestion in nose.
Some people is very sensitive to phenylephrine and following side effects occour.
1. Feeling dizzy.
2. Headache.
3. Upset stomach or throwing up.
4. Dry mouth.
5. excitability and nervousness.

If symptoms is severe, you can quit the drug.
You can try half the dose.

You should use topical nose drug: Oxymetazoline nasal drop.
No harm in cutting dose.
Addition to that:
1. Take steam inhalation 3-4 times a day for better result.
2. 1 % betadine garglling
3. Drink luke warm water
4. If fever take Tablet paracetamol 500 mg 2 times a day


Hope this may help you
Wish you good health
Best regards
Dr. Sagar
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What Causes Headaches While On Phenylephrine And Guaifenesin?

Hello dear Understand your concern. Phenylephrine is a act by stimulating alfa adreneric receptor. It cause vacoconstriction of nose blood vesseles and reduce inflammation & congestion in nose. Some people is very sensitive to phenylephrine and following side effects occour. 1. Feeling dizzy. 2. Headache. 3. Upset stomach or throwing up. 4. Dry mouth. 5. excitability and nervousness. If symptoms is severe, you can quit the drug. You can try half the dose. You should use topical nose drug: Oxymetazoline nasal drop. No harm in cutting dose. Addition to that: 1. Take steam inhalation 3-4 times a day for better result. 2. 1 % betadine garglling 3. Drink luke warm water 4. If fever take Tablet paracetamol 500 mg 2 times a day Hope this may help you Wish you good health Best regards Dr. Sagar