Respected user, hi I evaluated your query thoroughly. *You are having functional bowel disorder leading to chronic constipation & it has became duphalac resistant. *More will be of life style modifications giving you results slowly but long lasting not like duphalac. *Kindly manage certain very simple easy steps at home for better recovery - liquid intake to be at least 4 litres a day preferably boiled water, coconut water, rice water, lemon juice, green tea, home made juices, butter milk - diet should be very rich in green leafy vegetables, cereals, pulses, legumes yoggurt etc. - take adequate amounts of proteins , carbohydrates, vitamins, minerals , anti-oxidants , trace elements in intake by mouth. - avoid all oily / spicy / nonveg stuffs / beverages / pastas / cheese / excess ghee / sugar / sweeteners - chew your food very thoroughly which is neglected manytimes. - take small amounts of foods at intervals - fix timing of breakfast, lunch ,dinner - avoid sleeping atleast for 2 hours after lunch / dinner - avoid prolong fasting / overeating - do regular walking in fresh air, exercises at home with YOGA without failure for 1 hour a day. - keep ambulatory , energetic . - in our clinic we recommend certain natural products like Amla , Triphla, Isabgula husk for excellent results & Ultrasound Abdomen Pelvis +/- Colonoscopy in selected cases. Hope this clears your query. Thanks for using Health Care Magic & giving me an opportunity to assist you in the time of your medical help. Wishing you fine speedy recovery from the same. Regards dear take care.