Hello Dear I evaluated your query in depth . @ Breathing difficulty is in association with Cardio respiratory involvement with lung effusion & heart enlargement . @ Reason for pleural effusion is isolated entity or in concern with dialysis is a matter of evaluation in terms of possible fluid overload or compromised lung functions . @ Have to take intensive indoor physician treatment , nursing care in form of chest physiotherapy & other supportive treatment to get cured from the ailment . Hope this will help you definitely . Feel free to ask any further health related query . Thanks for using Health care magic . Regards .