Hi, Syndopa is a medication that contains two active ingredients, levodopa, and carbidopa, which are used to treat the symptoms of Parkinson s disease. Levodopa is converted to dopamine in the brain, which helps to alleviate symptoms such as tremors, stiffness, and difficulty with movement. Carbidopa helps to prevent the breakdown of levodopa in the bloodstream, allowing more levodopa to reach the brain. When someone stops taking Syndopa, they may experience a return of Parkinson s symptoms, which could include tremors, stiffness, difficulty with movement, and other symptoms that they experienced before starting the medication. This is because the medication helps to alleviate the symptoms of Parkinson s disease, but does not cure the disease itself. However, if the patient is not experiencing any adverse side effects, then stopping the medication for a week may be a reasonable approach to see how the patient responds without it. Rupark is another medication that is used to treat Parkinson s disease, and it contains the active ingredient ropinirole. Ropinirole works by stimulating dopamine receptors in the brain, which helps to alleviate symptoms of Parkinson s disease. If your mother is switching from Syndopa to Rupark, she may experience different side effects or a different response to the medication. She needs to talk to her neurologist about any concerns or questions she may have about her medications. Take care. Hope I have answered your question. Let me know if I can assist you further. Regards, Dr. Priyanka, General & Family Physician