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Suggest Treatment For Side Effects Of Propranolol
Hi, I was on propranolol (80mg/2xs/day) for over a year. I started noticing increasing weird side effects about 2 months ago (arms and legs going numb, tingling, pain in joints, feeling like I had mittens on, lack of fine motor skills) so I titrated myself off the medication with my doctor s help (have been off it now, for over a month). After that (about a month ago, I got a blood test back with elevated ALT and ASP). I don t drink alcohol and after this test, stopped taking any kind of pain killer (including tylenol). Last week, I also stopped taking antibiotics (minocycline) per my doctor s suggestion, with no effect on the tests. The levels have been doubling every week since then and are at AST=368 and ALT= 577. I have a ultrasound tomorrow and a gastroentologist appointment next week. Can anyone tell me what might be going on? Is it possible that the issue was the propranolol? The joint pain stopped entirely in the last week off of the antibiotics. My doctor thinks it might be autoimmune hepatitis (tests for Hep B and C came back negative) or a reaction to the antibiotics. Anything else we should consider? Also, I m 33, normal weight (125, 5 5 ), Caucasian, and female.
Tue, 12 Jul 2022
Hello,
You were on propranolol for a long period (over one year). you are experiencing numbness, tingling, pain in the joints, lack of motor movements, joint/muscle pain. The symptoms mentioned are due to side effects of propranolol, any medicine when taken in excessive dose over a period of time causes side effects/adverse effects. With the help of your treating doctor you should gradually reduce the dose and if needed your doctor should prescribe some other medicine that suits you better.
Your nerves have got affected, take food rich in vitamin B6, B12 or supplements. Get examined by a neurologist, get NCV test, blood works and imaging tests done to assess the degree of damage done to the nerves (neurological system). You will be treated accordingly. You have AST and ALT level elevated. Your AST and ALT levels are highly raised, it is indicative of developing liver problem. You are suggested to stay away from alcohol or addictions if any. Avoid fried food, oily or junk food. Do not take trans fat, full fat dairy products, red meat, food that is hard to digest.
Take boiled food with a dash of olive oil for a couple of months, repeat tests for AST and ALT, and other liver function tests every 45 days, slowly the levels will reduce provided you are on strict diet control and avoid all alcoholic drugs. Take liver tonics and enzymes (Aristozyme) to help digestion. You should get blood works, LFT, Urinalysis, blood for bile, and imaging tests to study the details of liver damage.
Alterations to both AST and ALT levels are normally indicative of liver injury, which can happen due to hepatitis, cirrhosis, or fatty liver. Your treating doctor should also prescribe other tests to check cardiac health, such as troponin, myoglobin and creatine phosphokinase (CPK) blood tests. You will be treated accordingly.
Take care. Hope I have answered your question. Let me know if I can assist you further.
Regards,
Dr. Nupur K., General & Family Physician
You were on propranolol for a long period (over one year). you are experiencing numbness, tingling, pain in the joints, lack of motor movements, joint/muscle pain. The symptoms mentioned are due to side effects of propranolol, any medicine when taken in excessive dose over a period of time causes side effects/adverse effects. With the help of your treating doctor you should gradually reduce the dose and if needed your doctor should prescribe some other medicine that suits you better.
Your nerves have got affected, take food rich in vitamin B6, B12 or supplements. Get examined by a neurologist, get NCV test, blood works and imaging tests done to assess the degree of damage done to the nerves (neurological system). You will be treated accordingly. You have AST and ALT level elevated. Your AST and ALT levels are highly raised, it is indicative of developing liver problem. You are suggested to stay away from alcohol or addictions if any. Avoid fried food, oily or junk food. Do not take trans fat, full fat dairy products, red meat, food that is hard to digest.
Take boiled food with a dash of olive oil for a couple of months, repeat tests for AST and ALT, and other liver function tests every 45 days, slowly the levels will reduce provided you are on strict diet control and avoid all alcoholic drugs. Take liver tonics and enzymes (Aristozyme) to help digestion. You should get blood works, LFT, Urinalysis, blood for bile, and imaging tests to study the details of liver damage.
Alterations to both AST and ALT levels are normally indicative of liver injury, which can happen due to hepatitis, cirrhosis, or fatty liver. Your treating doctor should also prescribe other tests to check cardiac health, such as troponin, myoglobin and creatine phosphokinase (CPK) blood tests. You will be treated accordingly.
Take care. Hope I have answered your question. Let me know if I can assist you further.
Regards,
Dr. Nupur K., General & Family Physician
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