I have small blister on my hands and the sole of one foot the blisters originally were filled with clear fluid and to the top of the skin but now seem to be deeper and pus filled my skin where affected is very dry and cracked although I use an anti bacterial cream constantly I was prescribed steroid cream which didn t help it did infact seem to make the skin worse although I was last week prescribed anti biotics and steroids for a chest infection my hands and foot cleared up almost completely but after the 2nd day of completing the antibiotics the blisters were back worse than ever